# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4059284 | B | Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting method | Rattus norvegicus | 41 | cell-based format | Scientific Literature | ||
2. | ALA4059285 | B | Displacement of [3H]epibatidine from rat alpha4beta4 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting method | Rattus norvegicus | 41 | cell-based format | Scientific Literature | ||
3. | ALA4059286 | B | Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting method | Rattus norvegicus | 41 | cell-based format | Scientific Literature | ||
4. | ALA4059287 | B | Selectivity ratio of Ki for rat alpha4beta4 nAChR to Ki for rat alpha4beta2 nAChR | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
5. | ALA4059288 | B | Selectivity ratio of Ki for rat alpha3beta4 nAChR to Ki for rat alpha4beta2 nAChR | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
6. | ALA4059289 | B | Potency index, ratio of DHbetaE Ki to test compound Ki for rat alpha4beta2 nAChR | Rattus norvegicus | 2 | protein complex format | Scientific Literature | ||
7. | ALA4059290 | B | Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up to 90 secs by FMP assay | Rattus norvegicus | 41 | cell-based format | Scientific Literature | ||
8. | ALA4059291 | B | Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up to 90 secs by FMP assay | Mus musculus | 41 | cell-based format | Scientific Literature | ||
9. | ALA4059293 | B | Agonist activity at human alpha7 nAChR expressed in HEK293 cells co-expressing Ric-3/NACHO assessed as induction of calcium mobilization measured up to 90 secs in presence of PNU-120596 by FLIPR assay | Homo sapiens | 24 | cell-based format | Scientific Literature |