| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3996878 | Functional | Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed as inhibition of quisqualate-induced inositol phosphate accumulation after 30 mins by HTRF assay | Rattus norvegicus | 7 | ALA3994627 | cell-based format | Scientific Literature | |
| 2. | ALA3996879 | Functional | Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed as inhibition of quisqualate-induced inositol phosphate accumulation after 30 mins by HTRF assay relative to fenobam | Rattus norvegicus | 6 | ALA3994627 | cell-based format | Scientific Literature | |
| 3. | ALA3996880 | Binding | Ratio of IC50 for negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells under dark condition to IC50 for negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells under violet light illumination | Rattus norvegicus | 7 | ALA3994627 | cell-based format | Scientific Literature | |
| 4. | ALA3996881 | Functional | Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed as inhibition of quisqualate-induced inositol phosphate accumulation by measuring difference in efficacy between dark condition and violet light illumination after 30 mins by HTRF assay | Rattus norvegicus | 7 | ALA3994627 | cell-based format | Scientific Literature |
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