# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4041386 | F | Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation after 2 hrs by AlphaScreen assay | Mus musculus | 24 | cell-based format | Scientific Literature | ||
2. | ALA4041391 | F | Agonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assay | Mus musculus | 21 | cell-based format | Scientific Literature | ||
3. | ALA4041392 | F | Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assay | Mus musculus | 22 | cell-based format | Scientific Literature | ||
4. | ALA4041394 | F | Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation after 2 hrs by AlphaScreen assay | Mus musculus | 24 | cell-based format | Scientific Literature | ||
5. | ALA4041395 | F | Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as increase in cAMP accumulation at 100 uM after 2 hrs by AlphaScreen assay relative to control | Mus musculus | 9 | cell-based format | Scientific Literature | ||
6. | ALA4041401 | F | Inverse agonist activity at mouse melanocortin receptor 5 expressed in HEK293 cells assessed as decrease in cAMP accumulation at 60 nM after 2 hrs by AlphaScreen assay relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA4357466 | F | Inverse agonist activity at human melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of basal cAMP accumulation incubated for 2 hrs by cAMP Alpha-screen assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
8. | ALA4357476 | F | Inverse agonist activity at mouse melanocortin receptor 5 expressed in HEK293 cells assessed as inhibition of basal cAMP accumulation incubated for 2 hrs by cAMP Alpha-screen assay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
9. | ALA4357478 | F | Antagonist activity at mouse melanocortin receptor 5 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated for 2 hrs by cAMP Alpha-screen assay based Schild analysis | Mus musculus | 10 | cell-based format | Scientific Literature | ||
10. | ALA4357479 | B | Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 1 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting method | Mus musculus | 11 | cell-based format | Scientific Literature | ||
11. | ALA4357482 | B | Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 3 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting method | Mus musculus | 11 | cell-based format | Scientific Literature | ||
12. | ALA4357485 | B | Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting method | Mus musculus | 11 | cell-based format | Scientific Literature | ||
13. | ALA4357488 | B | Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 5 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting method | Mus musculus | 11 | cell-based format | Scientific Literature | ||
14. | ALA4357491 | B | Displacement of [125I]-NDP-MSH from human melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting method | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
15. | ALA4731042 | F | Agonist activity at mouse MC1R at 100 uM by alphascreen cAMP assay relative to NDP-MSH | Mus musculus | 8 | assay format | Scientific Literature | ||
16. | ALA4731044 | F | Agonist activity at mouse MC3R at 100 uM by alphascreen cAMP assay relative to control | Mus musculus | 2 | assay format | Scientific Literature | ||
17. | ALA4731045 | F | Antagonist activity at mouse MC3R assessed as antagonist potency by alphascreen cAMP assay | Mus musculus | 13 | assay format | Scientific Literature | ||
18. | ALA4731046 | F | Agonist activity at mouse MC4R by alphascreen cAMP assay | Mus musculus | 14 | assay format | Scientific Literature | ||
19. | ALA4731047 | F | Antagonist activity at mouse MC4R assessed as antagonist potency by alphascreen cAMP assay | Mus musculus | 13 | assay format | Scientific Literature | ||
20. | ALA4731049 | F | Agonist activity at mouse MC5R at 100 uM by alphascreen cAMP assay relative to control | Mus musculus | 8 | assay format | Scientific Literature |