# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4048554 | B | Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followed by TNF and zVAD.fmk addition measured after 3 hrs by Hoechst 33342/propidium iodide staining-based assay | Mus musculus | 46 | ALA4043285 | cell-based format | Scientific Literature | |
2. | ALA4048556 | B | Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed by TNF and zVAD.fmk addition measured after 3 hrs by Hoechst 33342/propidium iodide staining-based assay | Mus musculus | 46 | ALA4043285 | cell-based format | Scientific Literature | |
3. | ALA4048557 | A | Inhibition of Aurk mouse L929sA cells transfected with human Fas assessed as reduction in cell growth after 24 hrs in presence of TNF by Hoechst 33342 staining-based microscopic assay | Mus musculus | 46 | ALA4043285 | assay format | Scientific Literature | |
4. | ALA4048558 | A | Inhibition of Aurk mouse L929sA cells transfected with human Fas assessed as increase in nuclear area after 24 hrs in presence of TNF by Hoechst 33342 staining-based microscopic assay | Mus musculus | 46 | ALA4043285 | assay format | Scientific Literature | |
5. | ALA4048559 | B | Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis at 3 uM pretreated for 0.5 hrs followed by TNF and zVAD.fmk addition measured after 3 hrs by Hoechst 33342/propidium iodide staining-based assay relative to control | Mus musculus | 34 | ALA4043285 | cell-based format | Scientific Literature | |
6. | ALA4048560 | B | Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis at 3 uM pretreated for 24 hrs followed by TNF and zVAD.fmk addition measured after 3 hrs by Hoechst 33342/propidium iodide staining-based assay relative to control | Mus musculus | 31 | ALA4043285 | cell-based format | Scientific Literature | |
7. | ALA4048562 | A | Inhibition of Aurk in mouse L929sA cells transfected with human Fas assessed as increase in nuclear area at 3 uM after 24 hrs in presence of TNF by Hoechst 33342 staining-based microscopic assay relative to control | Mus musculus | 40 | ALA4043285 | cell-based format | Scientific Literature |