| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4048554 | B | Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followed by TNF and zVAD.fmk addition measured after 3 hrs by Hoechst 33342/propidium iodide staining-based assay | Mus musculus | 46 | cell-based format | Scientific Literature | ||
| 2. | ALA4048556 | B | Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed by TNF and zVAD.fmk addition measured after 3 hrs by Hoechst 33342/propidium iodide staining-based assay | Mus musculus | 46 | cell-based format | Scientific Literature | ||
| 3. | ALA4048557 | A | Inhibition of Aurk mouse L929sA cells transfected with human Fas assessed as reduction in cell growth after 24 hrs in presence of TNF by Hoechst 33342 staining-based microscopic assay | Mus musculus | 46 | assay format | Scientific Literature | ||
| 4. | ALA4048558 | A | Inhibition of Aurk mouse L929sA cells transfected with human Fas assessed as increase in nuclear area after 24 hrs in presence of TNF by Hoechst 33342 staining-based microscopic assay | Mus musculus | 46 | assay format | Scientific Literature | ||
| 5. | ALA4048559 | B | Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis at 3 uM pretreated for 0.5 hrs followed by TNF and zVAD.fmk addition measured after 3 hrs by Hoechst 33342/propidium iodide staining-based assay relative to control | Mus musculus | 34 | cell-based format | Scientific Literature | ||
| 6. | ALA4048560 | B | Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis at 3 uM pretreated for 24 hrs followed by TNF and zVAD.fmk addition measured after 3 hrs by Hoechst 33342/propidium iodide staining-based assay relative to control | Mus musculus | 31 | cell-based format | Scientific Literature | ||
| 7. | ALA4048562 | A | Inhibition of Aurk in mouse L929sA cells transfected with human Fas assessed as increase in nuclear area at 3 uM after 24 hrs in presence of TNF by Hoechst 33342 staining-based microscopic assay relative to control | Mus musculus | 40 | cell-based format | Scientific Literature |
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