# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4013726 | B | Inhibition of human IL-15Ralpha-sushi domain/human IL-15-induced mouse 32D-beta cell proliferation preincubated for 30 mins with protein followed by cell addition measured after 2.5 days by Alamar blue reduction assay | Mus musculus | 51 | ALA4011646 | protein format | Scientific Literature | |
2. | ALA4013727 | B | Inhibition of recombinant human IL2R/IL2-induced mouse 32D-beta cell proliferation preincubated for 30 mins with protein followed by cell addition measured after 2.5 days by Alamar blue reduction assay | Homo sapiens | 51 | ALA4011646 | assay format | Scientific Literature | |
3. | ALA4013728 | B | Inhibition of IL15R/IL15 interaction in human NK92 cells assessed as reduction of IL15-induced STAT5 phosphorylation preincubated for 30 mins with IL15 followed by cell addition measured after 1 hr by AlphaScreen assay | Homo sapiens | 17 | ALA4011646 | cell-based format | Scientific Literature | |
4. | ALA4013729 | B | Inhibition of IL2R/IL2 interaction in human NK92 cells assessed as reduction IL2-induced STAT5 phosphorylation preincubated for 30 mins with IL2 followed by cell addition measured after 1 hr by AlphaScreen assay | Homo sapiens | 17 | ALA4011646 | cell-based format | Scientific Literature | |
5. | ALA4013730 | B | Binding affinity to recombinant human IL-15 by SPR assay | Homo sapiens | 17 | ALA4011646 | single protein format | Scientific Literature | |
6. | ALA4013731 | B | Binding affinity to recombinant human IL-2 by SPR assay | Homo sapiens | 17 | ALA4011646 | single protein format | Scientific Literature | |
7. | ALA4822545 | B | Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of RLI incubated for 30 mins followed by RLI addition and measured after 2.5 days by alamar blue assay | Mus musculus | 25 | ALA4819118 | cell-based format | Scientific Literature | |
8. | ALA4822546 | B | Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of IL2 incubated for 30 mins followed by IL2 addition and measured after 2.5 days by alamar blue assay | Mus musculus | 25 | ALA4819118 | cell-based format | Scientific Literature | |
9. | ALA4822547 | B | Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by alphascreen assay | Homo sapiens | 25 | ALA4819118 | cell-based format | Scientific Literature | |
10. | ALA4822548 | B | Inhibition of IL2-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by alphascreen assay | Homo sapiens | 25 | ALA4819118 | cell-based format | Scientific Literature | |
11. | ALA4822549 | B | Binding affinity to recombinant human IL-15 assessed as dissociation constant by SPR analysis | Homo sapiens | 7 | ALA4819118 | single protein format | Scientific Literature |