# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4022510 | Functional | Antiinflammatory activity in primary human endothelial keratinocytes assessed as inhibition of IL-17A/TNF-alpha induced IL-8 production preincubated for 2 hrs followed by cytokine addition measured after 72 hrs by HTRF assay | Homo sapiens | 12 | ALA4020800 | cell-based format | Scientific Literature | |
2. | ALA4022511 | Functional | Antiinflammatory activity in primary human endothelial keratinocytes assessed as inhibition of IL-17A/TNF-alpha induced IL-8 production at 10 uM preincubated for 2 hrs followed by cytokine addition measured after 72 hrs by HTRF assay relative to control | Homo sapiens | 13 | ALA4020800 | cell-based format | Scientific Literature | |
3. | ALA4022512 | ADME | Cytotoxicity against primary human endothelial keratinocytes assessed as inhibition of cell viability preincubated for 2 hrs followed by cytokine addition measured after 72 hrs by PrestoBlue staining based fluorescence assay | Homo sapiens | 13 | ALA4020800 | cell-based format | Scientific Literature | |
4. | ALA4022513 | ADME | Cytotoxicity against primary human endothelial keratinocytes assessed as inhibition of cell viability at 10 uM preincubated for 2 hrs followed by cytokine addition measured after 72 hrs by PrestoBlue staining based fluorescence assay relative to control | Homo sapiens | 12 | ALA4020800 | cell-based format | Scientific Literature | |
5. | ALA4022514 | Functional | Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNF-alpha production after 16 hrs by AlphaLisa assay | Homo sapiens | 12 | ALA4020800 | cell-based format | Scientific Literature |