# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA685507 | Binding | In vitro inhibition of human Glutathione Reductase | 4 | ALA1134294 | single protein format | Scientific Literature | ||
2. | ALA681184 | Binding | Competitive inhibition of human Glutathione Reductase | 4 | ALA1134294 | single protein format | Scientific Literature | ||
3. | ALA704873 | Functional | In vitro antiparasitic activity against Leishmania donovani was tested by sigmoidal regression analysis | Leishmania donovani | 59 | ALA1134791 | assay format | Scientific Literature | |
4. | ALA753358 | Functional | Effective dose against chloroquine-resistant Plasmodium falciparum FcB1R | Plasmodium falciparum | 10 | ALA1134294 | organism-based format | Scientific Literature | |
5. | ALA767201 | Binding | In vitro inhibition of Plasmodium falciparum Glutathione Reductase | Plasmodium falciparum FcB1 | 4 | ALA1134294 | single protein format | Scientific Literature | |
6. | ALA767203 | Binding | Competitive inhibition of Plasmodium falciparum Glutathione Reductase | Plasmodium falciparum FcB1 | 2 | ALA1134294 | single protein format | Scientific Literature | |
7. | ALA808704 | Functional | In vitro antiparasitic activity against Trypanosoma brucei was tested by sigmoidal regression analysis | Trypanosoma brucei | 75 | ALA1134791 | organism-based format | Scientific Literature | |
8. | ALA809368 | Functional | In vitro antiparasitic activity against Trypanosoma cruzi was tested by sigmoidal regression analysis | Trypanosoma cruzi | 62 | ALA1134791 | organism-based format | Scientific Literature | |
9. | ALA812446 | Binding | Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 uM T(S)2. | Trypanosoma cruzi | 77 | ALA1134791 | single protein format | Scientific Literature | |
10. | ALA839924 | Binding | Inhibitory concentration against human glutathione reductase | Homo sapiens | 1 | ALA1138849 | single protein format | Scientific Literature | |
11. | ALA876366 | Binding | Inhibitory concentration against Plasmodium falciparum glutathione reductase | Plasmodium falciparum | 1 | ALA1138849 | single protein format | Scientific Literature | |
12. | ALA830922 | Binding | Inhibitory concentration against human glutathione reductase | Homo sapiens | 1 | ALA1138849 | single protein format | Scientific Literature | |
13. | ALA828426 | Binding | Inhibitory concentration against Plasmodium falciparum glutathione reductase | Plasmodium falciparum | 4 | ALA1138849 | single protein format | Scientific Literature | |
14. | ALA827279 | Binding | Inhibitory concentration against human glutathione reductase in the presence of 200 uM exogenous NADP | Homo sapiens | 1 | ALA1138849 | single protein format | Scientific Literature | |
15. | ALA832300 | Binding | Inhibitory concentration against human glutathione reductase in the absence of glucose-6-phosphate dehydrogenase (G6PDH) | Homo sapiens | 1 | ALA1138849 | single protein format | Scientific Literature | |
16. | ALA833255 | Functional | Inhibitory concentration against Plasmodium falciparum FcBIR | Plasmodium falciparum | 11 | ALA1138849 | organism-based format | Scientific Literature | |
17. | ALA826831 | Functional | Cytotoxicity against human diploid embryonic lung cell line hMRC-5 was observed at conc. upto 32 uM; (No cytotoxicity) | Homo sapiens | 11 | ALA1138849 | cell-based format | Scientific Literature | |
18. | ALA4480667 | Functional | Cytoprotection against rotenone-induced mitochondrial dysfunction in human HepG2 cells assessed as increase in cell viability by measuring ATP levels at 10 uM preincubated for 48 hrs followed by rotenone-induction and measured after 24 hrs by luciferase-based assay | Homo sapiens | 27 | ALA4480378 | cell-based format | Scientific Literature | |
19. | ALA4480670 | Functional | Cytoprotection against rotenone-induced mitochondrial dysfunction in human HepG2 cells assessed as acute ATP rescue at 10 uM co-treated with rotenone for 1 hr by luciferase-based assay relative to control | Homo sapiens | 34 | ALA4480378 | cell-based format | Scientific Literature |