# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4018533 | Binding | Binding affinity to N-terminal NT-647-NHS labeled NM23-H2 F60A mutant (unknown origin) up to 50 uM by SPR analysis | Homo sapiens | 1 | ALA4017489 | assay format | Scientific Literature | |
2. | ALA4018534 | Binding | Binding affinity to NM23-H2 in human SiHa cells assessed as decrease in NM23-H2 to c-myc G-quadruplex DNA interaction after 9 hrs by Chromatin immunoprecipitation assay | Homo sapiens | 1 | ALA4017489 | cell-based format | Scientific Literature | |
3. | ALA4018535 | Functional | Antitumor activity against human SiHa cells xenografted in BALB/C nude mouse assessed as tumor growth inhibition at 2.5 mg/kg, ip administered daily after 3 weeks relative to control | Homo sapiens | 1 | ALA4017489 | organism-based format | Scientific Literature | |
4. | ALA4018536 | Binding | Binding affinity to NM23-H2 F60A mutant (unknown origin) up to 50 uM by SPR analysis | Homo sapiens | 1 | ALA4017489 | assay format | Scientific Literature | |
5. | ALA4018537 | Functional | Antimigratory activity against human SiHa cells assessed as reduction in wound closure by microscopic method | Homo sapiens | 1 | ALA4017489 | cell-based format | Scientific Literature | |
6. | ALA4018538 | Binding | Binding affinity to NM23-H2 (unknown origin) by SPR analysis | Homo sapiens | 31 | ALA4017489 | single protein format | Scientific Literature | |
7. | ALA4018539 | Binding | Binding affinity to N-terminal NT-647-NHS labeled NM23-H2 (unknown origin) after 30 mins by MST analysis | Homo sapiens | 47 | ALA4017489 | single protein format | Scientific Literature | |
8. | ALA4018540 | Binding | Binding affinity to NM23-H2 D54A mutant (unknown origin) by SPR analysis | Homo sapiens | 1 | ALA4017489 | assay format | Scientific Literature | |
9. | ALA4018541 | Binding | Binding affinity to N-terminal NT-647-NHS labeled NM23-H2 D54A mutant (unknown origin) after 30 mins by MST analysis | Homo sapiens | 1 | ALA4017489 | assay format | Scientific Literature | |
10. | ALA4018542 | Binding | Binding affinity to NM23-H2 G113F mutant (unknown origin) by SPR analysis | Homo sapiens | 1 | ALA4017489 | assay format | Scientific Literature | |
11. | ALA4018543 | Binding | Binding affinity to N-terminal NT-647-NHS labeled NM23-H2 G113F mutant (unknown origin) after 30 mins by MST analysis | Homo sapiens | 1 | ALA4017489 | assay format | Scientific Literature | |
12. | ALA4018544 | Binding | Binding affinity to NM23-H2 H118F mutant (unknown origin) by SPR analysis | Homo sapiens | 1 | ALA4017489 | assay format | Scientific Literature | |
13. | ALA4018545 | Binding | Binding affinity to N-terminal NT-647-NHS labeled NM23-H2 H118F mutant (unknown origin) after 30 mins by MST analysis | Homo sapiens | 1 | ALA4017489 | assay format | Scientific Literature | |
14. | ALA4018546 | Binding | Binding affinity to N-terminal NT-647-NHS labeled NM23-H2 D121A mutant (unknown origin) after 30 mins by MST analysis | Homo sapiens | 1 | ALA4017489 | assay format | Scientific Literature | |
15. | ALA4018547 | Binding | Binding affinity to 5'-FAM/3'-TAMRA labeled Pu22 c-myc G-quadruplex DNA (unknown origin) assessed as increase in melting temperature at 1 uM by FRET assay | Not specified | 1 | ALA4017489 | assay format | Scientific Literature | |
16. | ALA4018548 | Binding | Binding affinity to biotin-labeled Pu22 c-myc G-quadruplex DNA (unknown origin) at 40 uM after 30 mins by SPR analysis | Not specified | 1 | ALA4017489 | assay format | Scientific Literature | |
17. | ALA4018549 | Binding | Binding affinity to Htg21 telomeric G-quadruplex DNA (unknown origin) at 40 uM after 30 mins by SPR analysis | Not specified | 47 | ALA4017489 | assay format | Scientific Literature | |
18. | ALA4018550 | Binding | Binding affinity to biotin-labeled 18-mer duplex DNA hairpin (unknown origin) at 40 uM after 30 mins by SPR analysis | Not specified | 47 | ALA4017489 | assay format | Scientific Literature | |
19. | ALA4018551 | Binding | Binding affinity to NM23-H2 (unknown origin) assessed as ratio of Kd for protein interaction with biotin-labeled Pu22 c-myc G-quadruplex DNA in presence and absence of compound after 1 hr by ELISA | Homo sapiens | 17 | ALA4017489 | single protein format | Scientific Literature | |
20. | ALA4018552 | Binding | Binding affinity to NM23-H2 (unknown origin) assessed as reduction in protein interaction with Pu22 c-myc G-quadruplex DNA after 1 hr by EMSA | Homo sapiens | 1 | ALA4017489 | single protein format | Scientific Literature |