# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4040247 | ADME | Half life in mouse liver microsomes | Mus musculus | 14 | ALA4038316 | assay format | Scientific Literature | |
2. | ALA4040248 | ADME | Intrinsic clearance in mouse liver microsomes assessed per mg of protein | Mus musculus | 14 | ALA4038316 | assay format | Scientific Literature | |
3. | ALA4040249 | ADME | Half life in mouse liver microsomes in absence of NADPH | Mus musculus | 3 | ALA4038316 | assay format | Scientific Literature | |
4. | ALA4040251 | Functional | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 infected in human RBC after 48 hrs by YOYO-1 staining-based flow cytometry method | Plasmodium falciparum | 20 | ALA4038316 | assay format | Scientific Literature | |
5. | ALA4040253 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 4 mg/kg/day administered for 4 days via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 20 | ALA4038316 | organism-based format | Scientific Literature | |
6. | ALA4040254 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 1 mg/kg/day administered for 4 days via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 4 | ALA4038316 | organism-based format | Scientific Literature | |
7. | ALA4040255 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 6 mg/kg/day administered for 4 days via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 20 | ALA4038316 | organism-based format | Scientific Literature | |
8. | ALA4040258 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 0.5 mg/kg/day administered for 4 days via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 2 | ALA4038316 | organism-based format | Scientific Literature | |
9. | ALA4040259 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 2 mg/kg/day administered for 4 days via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 2 | ALA4038316 | organism-based format | Scientific Literature | |
10. | ALA4040260 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 4 mg/kg/day administered for 3 days via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 2 | ALA4038316 | organism-based format | Scientific Literature | |
11. | ALA4040261 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 4 mg/kg/day administered for 2 days via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 2 | ALA4038316 | organism-based format | Scientific Literature | |
12. | ALA4040262 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 4 mg/kg/day administered for 1 day via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 2 | ALA4038316 | organism-based format | Scientific Literature | |
13. | ALA4040263 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 40 mg/kg/day administered for 1 day via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 3 | ALA4038316 | organism-based format | Scientific Literature | |
14. | ALA4040264 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 80 mg/kg/day administered for 1 day via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 3 | ALA4038316 | organism-based format | Scientific Literature | |
15. | ALA4040265 | Functional | Antiplasmodial activity against Plasmodium berghei infected in Swiss Webster mouse assessed as cure rate at 40 mg/kg/day administered for 2 days via oral gavage starting at 1 hr post infection measured after 30 days relative to control | Plasmodium berghei | 2 | ALA4038316 | organism-based format | Scientific Literature |