| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4043313 | B | Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate addition by spectrophotometric method | Homo sapiens | 17 | ALA4043061 | single protein format | Scientific Literature | |
| 2. | ALA4305239 | B | Inhibition of human neutrophil elastase at 200 uM using S1384 as substrate preincubated for 5 mins followed by substrate addition relative to control | Homo sapiens | 60 | ALA4304745 | single protein format | Scientific Literature | |
| 3. | ALA4305240 | B | Inhibition of human neutrophil elastase using S1384 as substrate preincubated for 5 mins followed by substrate addition | Homo sapiens | 23 | ALA4304745 | single protein format | Scientific Literature | |
| 4. | ALA4305241 | B | Inhibition of human neutrophil elastase using S1384 as substrate preincubated for 5 mins followed by substrate addition relative to control | Homo sapiens | 23 | ALA4304745 | single protein format | Scientific Literature | |
| 5. | ALA4305242 | B | Mixed type inhibition of human neutrophil elastase assessed as Vmax for substrate at 250 uM using varying levels of S1384 as substrate by Michaelis-Menten plot analysis (Rvb = 40.1 +/- 0.5 mAU/min) | Homo sapiens | 1 | ALA4304745 | single protein format | Scientific Literature | |
| 6. | ALA4305243 | B | Mixed type inhibition of human neutrophil elastase assessed as Vmax for substrate at 500 uM using varying levels of S1384 as substrate by Michaelis-Menten plot analysis (Rvb = 40.1 +/- 0.5 mAU/min) | Homo sapiens | 1 | ALA4304745 | single protein format | Scientific Literature | |
| 7. | ALA4305244 | B | Mixed type inhibition of human neutrophil elastase assessed as Vmax for substrate at 750 uM using varying levels of S1384 as substrate by Michaelis-Menten plot analysis (Rvb = 40.1 +/- 0.5 mAU/min) | Homo sapiens | 1 | ALA4304745 | single protein format | Scientific Literature | |
| 8. | ALA4305245 | B | Mixed type inhibition of human neutrophil elastase assessed as Vmax for substrate at 1000 uM using varying levels of S1384 as substrate by Michaelis-Menten plot analysis (Rvb = 40.1 +/- 0.5 mAU/min) | Homo sapiens | 1 | ALA4304745 | single protein format | Scientific Literature | |
| 9. | ALA4305246 | B | Mixed type inhibition of human neutrophil elastase assessed as Km for substrate at 250 uM using varying levels of S1384 as substrate by Michaelis-Menten plot analysis (Rvb = 650 +/- 24 uM) | Homo sapiens | 1 | ALA4304745 | single protein format | Scientific Literature | |
| 10. | ALA4305247 | B | Mixed type inhibition of human neutrophil elastase assessed as Km for substrate at 500 uM using varying levels of S1384 as substrate by Michaelis-Menten plot analysis (Rvb = 650 +/- 24 uM) | Homo sapiens | 1 | ALA4304745 | single protein format | Scientific Literature | |
| 11. | ALA4305248 | B | Mixed type inhibition of human neutrophil elastase assessed as Km for substrate at 750 uM using varying levels of S1384 as substrate by Michaelis-Menten plot analysis (Rvb = 650 +/- 24 uM) | Homo sapiens | 1 | ALA4304745 | single protein format | Scientific Literature | |
| 12. | ALA4305249 | B | Mixed type inhibition of human neutrophil elastase assessed as Km for substrate at 1000 uM using varying levels of S1384 as substrate by Michaelis-Menten plot analysis (Rvb = 650 +/- 24 uM) | Homo sapiens | 1 | ALA4304745 | single protein format | Scientific Literature | |
| 13. | ALA4305250 | B | Mixed type inhibition of human neutrophil elastase assessed as decrease in Vmax for substrate at 1000 uM using varying levels of S1384 as substrate by Michaelis-Menten plot analysis relative to control | Homo sapiens | 1 | ALA4304745 | single protein format | Scientific Literature | |
| 14. | ALA4305251 | B | Mixed type inhibition of human neutrophil elastase assessed as increase in Km for substrate at 1000 uM using varying levels of S1384 as substrate by Michaelis-Menten plot analysis relative to control | Homo sapiens | 1 | ALA4304745 | single protein format | Scientific Literature | |
| 15. | ALA4305252 | B | Inhibition of human neutrophil elastase using S1384 as substrate preincubated for 5 mins followed by substrate addition measured in presence of 362.5 mM NaCl | Homo sapiens | 9 | ALA4304745 | single protein format | Scientific Literature | |
| 16. | ALA4305254 | B | Inhibition of human neutrophil elastase using S1384 as substrate preincubated for 5 mins followed by substrate addition measured in presence of 2.1% v/v NaCl | Homo sapiens | 9 | ALA4304745 | single protein format | Scientific Literature | |
| 17. | ALA4305255 | B | Inhibition of human neutrophil elastase assessed as reduction in elastin-congo red hydrolysis preincubated for 30 mins followed by elastin-congo red addition measured up to 4 hrs relative to control | Homo sapiens | 4 | ALA4304745 | single protein format | Scientific Literature | |
| 18. | ALA4305257 | B | Inhibition of human neutrophil elastase assessed as reduction in elastin-congo red hydrolysis preincubated for 30 mins followed by elastin-congo red addition measured after 48 hrs | Homo sapiens | 2 | ALA4304745 | single protein format | Scientific Literature | |
| 19. | ALA4305258 | A | Anticoagulant activity in human plasma assessed as effect on activated partial thromboplastin time at 855 uM measured after 5 mins | Homo sapiens | 1 | ALA4304745 | cell-free format | Scientific Literature | |
| 20. | ALA4305259 | A | Anticoagulant activity in human plasma assessed as effect on prothrombin time at 855 uM measured after 5 mins | Homo sapiens | 1 | ALA4304745 | cell-free format | Scientific Literature |
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