# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4046117 | Functional | Antiproliferative activity against human AGS cells after 72 hrs by MTT assay | Homo sapiens | 5 | ALA4043169 | cell-based format | Scientific Literature | |
2. | ALA4046118 | Binding | Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate after 30 mins in presence of ATP by TR-FRET assay | Homo sapiens | 19 | ALA4043169 | assay format | Scientific Literature | |
3. | ALA4046119 | ADME | Clearance in mouse at 5 mg/kg, iv | Mus musculus | 1 | ALA4043169 | organism-based format | Scientific Literature | |
4. | ALA4046120 | ADME | Cmax in mouse at 5 mg/kg, iv | Mus musculus | 1 | ALA4043169 | organism-based format | Scientific Literature | |
5. | ALA4046121 | ADME | Cmax in mouse at 25 mg/kg, po | Mus musculus | 1 | ALA4043169 | organism-based format | Scientific Literature | |
6. | ALA4046122 | ADME | Tmax in mouse at 25 mg/kg, po | Mus musculus | 1 | ALA4043169 | organism-based format | Scientific Literature | |
7. | ALA4046123 | ADME | Half life in mouse at 5 mg/kg, iv | Mus musculus | 1 | ALA4043169 | organism-based format | Scientific Literature | |
8. | ALA4046124 | ADME | Half life in mouse at 25 mg/kg, po | Mus musculus | 1 | ALA4043169 | organism-based format | Scientific Literature | |
9. | ALA4046125 | ADME | Volume of distribution at steady state in mouse at 5 mg/kg, iv | Mus musculus | 1 | ALA4043169 | organism-based format | Scientific Literature | |
10. | ALA4046126 | ADME | Oral bioavailability in mouse at 25 mg/kg | Mus musculus | 1 | ALA4043169 | organism-based format | Scientific Literature |