#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4053808	Functional	Selectivity ratio of IC50 for human NCI-H1975 cells harboring EGFR L858R/T790M double mutant to IC50 for human A431 cells harboring wild-type EGFR	Homo sapiens	10	ALA4052618	assay format	Scientific Literature
2.	ALA4053809	Functional	Antiproliferative activity against human NCI-H1975 cells harboring EGFR L858R/T790M double mutant	Homo sapiens	10	ALA4052618	cell-based format	Scientific Literature
3.	ALA4053810	ADME	Inhibition of human recombinant cytoplasmic GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubated for 15 mins followed by substrate addition measured after 60 mins by FRET-based Z'-Lyte assay	Homo sapiens	21	ALA4052618	assay format	Scientific Literature
4.	ALA4053811	Binding	Inhibition of human recombinant cytoplasmic GST-tagged EGFR L858R mutant expressed in baculovirus using TK-substrate-biotin preincubated for 15 mins followed by substrate addition measured after 60 mins by FRET-based Z'-Lyte assay	Homo sapiens	21	ALA4052618	assay format	Scientific Literature
5.	ALA4053812	Binding	Inhibition of human recombinant cytoplasmic GST-tagged EGFR T790M/L858R double mutant (668 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubated for 15 mins followed by substrate addition measured after 60 mins by FRET-based Z'-Lyte assay	Homo sapiens	21	ALA4052618	assay format	Scientific Literature
6.	ALA4053813	Binding	Selectivity ratio of IC50 for human recombinant cytoplasmic GST-tagged EGFR (668 to 1210 residues) to IC50 for human recombinant cytoplasmic GST-tagged EGFR T790M/L858R double mutant (668 to 1210 residues)	Homo sapiens	19	ALA4052618	assay format	Scientific Literature
7.	ALA4053814	Functional	Antiproliferative activity against human A431 cells harboring wild-type EGFR	Homo sapiens	10	ALA4052618	cell-based format	Scientific Literature
8.	ALA4053815	Functional	Antiproliferative activity against human HCC827 cells harboring EGFR E746-A750 deletion mutant	Homo sapiens	10	ALA4052618	cell-based format	Scientific Literature
9.	ALA4053816	ADME	Half life in human liver microsomes	Homo sapiens	2	ALA4052618	assay format	Scientific Literature
10.	ALA4053817	ADME	Half life in mouse liver microsomes	Mus musculus	2	ALA4052618	assay format	Scientific Literature
11.	ALA4053818	ADME	Half life in rat liver microsomes	Rattus norvegicus	2	ALA4052618	assay format	Scientific Literature
12.	ALA4053819	ADME	Half life in dog liver microsomes	Canis lupus familiaris	2	ALA4052618	assay format	Scientific Literature
13.	ALA4053820	ADME	Half life in monkey liver microsomes	Macaca mulatta	2	ALA4052618	assay format	Scientific Literature
14.	ALA4053821	ADME	Intrinsic clearance in human liver microsomes	Homo sapiens	2	ALA4052618	assay format	Scientific Literature
15.	ALA4053822	ADME	Intrinsic clearance in mouse liver microsomes	Mus musculus	2	ALA4052618	assay format	Scientific Literature
16.	ALA4053823	ADME	Intrinsic clearance in rat liver microsomes	Rattus norvegicus	2	ALA4052618	assay format	Scientific Literature
17.	ALA4053824	ADME	Intrinsic clearance in dog liver microsomes	Canis lupus familiaris	2	ALA4052618	assay format	Scientific Literature
18.	ALA4053825	ADME	Intrinsic clearance in monkey liver microsomes	Macaca mulatta	2	ALA4052618	assay format	Scientific Literature
19.	ALA4053826	ADME	Half life in human hepatocytes	Homo sapiens	2	ALA4052618	cell-based format	Scientific Literature
20.	ALA4053827	ADME	Half life in rat hepatocytes	Rattus norvegicus	2	ALA4052618	cell-based format	Scientific Literature