# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4020039 | Binding | Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assay | Homo sapiens | 24 | ALA4017527 | single protein format | Scientific Literature | |
2. | ALA4020040 | Binding | Binding affinity to biotin labelled human EED (78 to 441 residues) assessed as association rate constant by SPR assay | Homo sapiens | 9 | ALA4017527 | single protein format | Scientific Literature | |
3. | ALA4020041 | Binding | Binding affinity to biotin labelled human EED (78 to 441 residues) assessed as dissociation rate constant by SPR assay | Homo sapiens | 9 | ALA4017527 | single protein format | Scientific Literature | |
4. | ALA4020042 | Binding | Binding affinity to biotin labelled human EED (78 to 441 residues) by SPR assay | Homo sapiens | 21 | ALA4017527 | single protein format | Scientific Literature | |
5. | ALA4138823 | Binding | Inhibition of GST-tagged EED (unknown origin) after 1 hr by OG(488) as probe-based TR-FRET analysis | Homo sapiens | 1 | ALA4138076 | single protein format | Scientific Literature | |
6. | ALA4138824 | Binding | Inhibition of PRC2 (unknown origin) after 70 mins in presence of [3H]SAM by TopCount method | Homo sapiens | 1 | ALA4138076 | assay format | Scientific Literature | |
7. | ALA4138825 | Functional | Antitumor activity against human Pfeiffer-FP1 cells xenografted in C.B.-17 SCID-Beige mouse at 300 mg/kg, sc administered for two times per week for 5 weeks relative to control | Homo sapiens | 1 | ALA4138076 | organism-based format | Scientific Literature | |
8. | ALA4613079 | Functional | Growth inhibition of human Pfeiffer cells incubated for 10 days by WST8 assay | Homo sapiens | 1 | ALA4610126 | cell-based format | Scientific Literature | |
9. | ALA4613080 | Functional | Antitumor activity against human Pfeiffer cells xenografted in mouse assessed as inhibition of tumor growth at 300 mg/kg, sc dosed twice per week for 5 weeks | Homo sapiens | 1 | ALA4610126 | organism-based format | Scientific Literature | |
10. | ALA4650107 | Binding | Thermal Shift Assay. Domain start/stop: M626-G740 | Homo sapiens | 1,014 | ALA4649998 | single protein format | EUbOPEN Chemogenomic Library | |
11. | ALA4725212 | Toxicity | Incucyte cell viability with HEK293T | Homo sapiens | 1,713 | ALA4689842 | cell-based format | EUbOPEN Chemogenomic Library | |
12. | ALA4725213 | Toxicity | Incucyte cell viability with human fibroblast | Homo sapiens | 1,718 | ALA4689842 | cell-based format | EUbOPEN Chemogenomic Library | |
13. | ALA4725214 | Toxicity | Incucyte cell viability with U2OS | Homo sapiens | 1,712 | ALA4689842 | cell-based format | EUbOPEN Chemogenomic Library | |
14. | ALA4735353 | Binding | Displacement of OG(488) labeled probe from GST-tagged EED (unknown origin) incubated for 1 hr by lanthaScreen TR-FRET method | Homo sapiens | 2 | ALA4732117 | single protein format | Scientific Literature | |
15. | ALA4735355 | Binding | Binding affinity to EED (unknown origin) by surface plasmon resonance analysis | Homo sapiens | 1 | ALA4732117 | single protein format | Scientific Literature | |
16. | ALA4735356 | Functional | Antiproliferative activity against human Pfeiffer cells incubated for 10 days by cellTiter-glo luminesence method | Homo sapiens | 1 | ALA4732117 | cell-based format | Scientific Literature | |
17. | ALA4735357 | Functional | Antitumor activity against human Pfeiffer-FP1 cells xenografted in CB17 scid-beige mouse assessed as tumor growth inhibition at 300 mg/kg, SC administered two times per week for 5 weeks by digital caliper method | Homo sapiens | 1 | ALA4732117 | organism-based format | Scientific Literature | |
18. | ALA4828519 | Functional | Growth inhibition of human KARPAS-422 cells assessed as cell growth incubated for 7 days by lactate dehydrogenase based WST-8 assay | Homo sapiens | 35 | ALA4825765 | cell-based format | Scientific Literature | |
19. | ALA4828520 | Binding | Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mins followed by H3K27Me3 addition and measured after 30 mins by alphascreen competition binding assay | Homo sapiens | 35 | ALA4825765 | single protein format | Scientific Literature | |
20. | ALA5060015 | Binding | Thermal Shift Assay. Domain: start/stop: S229-K512 | Homo sapiens | 1,499 | ALA5060014 | single protein format | EUbOPEN Chemogenomic Library |