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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4011333 | B | Enhancing of [3H]WIN35,428 binding to recombinant human DAT expressed in HEK293 cell membranes at 10 uM pre-incubated for 10 mins before radioligand addition and measured 90 mins after radioligand addition by micro beta scintillation counting analysis relative to control | Homo sapiens | 20 | ALA4007505 | cell-based format | Scientific Literature | |
2. | ALA4011334 | B | Inhibition of [3H]WIN35,428 binding to recombinant human DAT expressed in HEK293 cell membranes at 10 uM pre-incubated for 10 mins before radioligand addition and measured 90 mins after radioligand addition by micro beta scintillation counting analysis relative to control | Homo sapiens | 20 | ALA4007505 | cell-based format | Scientific Literature | |
3. | ALA4011335 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human A3AR expressed in HEK293T cells pre-incubated for 10 mins before radioligand addition and measured 90 mins after radioligand addition by micro beta scintillation counting analysis relative to control | Homo sapiens | 19 | ALA4007505 | cell-based format | Scientific Literature | |
4. | ALA4011336 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from mouse A3AR expressed in HEK293T cells pre-incubated for 10 mins before radioligand addition and measured 90 mins after radioligand addition by micro beta scintillation counting analysis relative to control | Mus musculus | 5 | ALA4007505 | cell-based format | Scientific Literature | |
5. | ALA4011340 | B | Enhancing of [125I]RTI-55 binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
6. | ALA4011341 | B | Enhancing of [3H]mazindol binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
7. | ALA4011342 | B | Enhancing of [125I]RTI-55 binding to recombinant human NET expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
8. | ALA4011343 | B | Inhibition of recombinant human DAT expressed in HEK293 cell membranes assessed as reduction in [3H]-DA uptake incubated for 22 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
9. | ALA4011344 | B | Enhancing of [3H]mazindol binding to recombinant human NET expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 12 | ALA4007505 | cell-based format | Scientific Literature | |
10. | ALA4011345 | B | Inhibition of recombinant human NET expressed in HEK293 cell membranes assessed as reduction in [3H]-norepinephrine uptake incubated for 22 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
11. | ALA4011346 | B | Enhancing of [125I]RTI-55 binding to recombinant human SERT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
12. | ALA4011347 | B | Enhancing of [3H]mazindol binding to recombinant human SERT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 10 | ALA4007505 | cell-based format | Scientific Literature | |
13. | ALA4011348 | B | Inhibition of recombinant human SERT expressed in HEK293 cell membranes assessed as reduction in [3H]5-HT uptake incubated for 22 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
14. | ALA4011358 | B | Inhibition of [125I]RTI-55 binding to recombinant human SERT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 21 | ALA4007505 | cell-based format | Scientific Literature | |
15. | ALA4011359 | B | Inhibition of [3H]mazindol binding to recombinant human SERT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 22 | ALA4007505 | cell-based format | Scientific Literature |