#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4049570	Toxicity	Toxicity in nude mouse xenografted with human OS-RC-2 cells assessed as body weight loss at 1.5 mg/kg, iv administered three times a week measured after 32 days (Rvb = 33%)	Mus musculus	1	ALA4049384	organism-based format	Scientific Literature
2.	ALA4049572	Physicochemical	Solubility of the compound in water		2	ALA4049384	small-molecule physicochemical format	Scientific Literature
3.	ALA4049573	Functional	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	Homo sapiens	2	ALA4049384	cell-based format	Scientific Literature
4.	ALA4049574	Functional	Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay	Homo sapiens	2	ALA4049384	cell-based format	Scientific Literature
5.	ALA4049575	Functional	Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay	Homo sapiens	2	ALA4049384	cell-based format	Scientific Literature
6.	ALA4049576	Functional	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	Homo sapiens	2	ALA4049384	cell-based format	Scientific Literature
7.	ALA4049577	Functional	Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by MTT assay	Homo sapiens	2	ALA4049384	cell-based format	Scientific Literature
8.	ALA4049578	ADME	Prodrug conversion in rat serum assessed as everolimus formation after 4 hrs by HPLC analysis	Rattus norvegicus	1	ALA4049384	cell-free format	Scientific Literature
9.	ALA4049579	ADME	Prodrug conversion in Sprague-Dawley rat blood assessed as everolimus formation at 2 mg/kg, iv after 2 hrs by HPLC analysis	Rattus norvegicus	1	ALA4049384	organism-based format	Scientific Literature
10.	ALA4049581	Functional	Antitumor activity against human OS-RC2 cells xenografted in nude mouse assessed as tumor weight at 1.5 mg/kg, iv administered three times a week measured after 32 days (Rvb = 0.68 +/- 0.06 g)	Homo sapiens	1	ALA4049384	organism-based format	Scientific Literature
11.	ALA4049582	Functional	Antitumor activity against human OS-RC2 cells xenografted in nude mouse assessed as tumor weight at 24 mg/kg, iv administered once weekly measured after 32 days (Rvb = 0.68 +/- 0.06 g)	Homo sapiens	1	ALA4049384	organism-based format	Scientific Literature
12.	ALA4049584	Functional	Antitumor activity against human OS-RC2 cells xenografted in nude mouse assessed as tumor growth inhibition at 1.5 mg/kg, iv administered three times a week measured after 32 days relative to control	Homo sapiens	1	ALA4049384	organism-based format	Scientific Literature
13.	ALA4049585	Functional	Antitumor activity against human OS-RC2 cells xenografted in nude mouse assessed as tumor growth inhibition at 24 mg/kg, iv administered once weekly measured after 32 days relative to control	Homo sapiens	1	ALA4049384	organism-based format	Scientific Literature
14.	ALA4049586	Toxicity	Toxicity in nude mouse xenografted with human OS-RC-2 cells assessed as body weight loss at 24 mg/kg, iv administered once weekly measured after 32 days (Rvb = 33%)	Mus musculus	1	ALA4049384	organism-based format	Scientific Literature
15.	ALA4049587	ADME	Prodrug conversion in rat assessed as everolimus formation by measuring everolimus AUC at 2 mg/kg, iv	Rattus norvegicus	1	ALA4049384	organism-based format	Scientific Literature
16.	ALA4049588	ADME	AUC (0 to infinity) in Sprague-Dawley rat at 2.724 mg/kg, iv	Rattus norvegicus	1	ALA4049384	organism-based format	Scientific Literature
17.	ALA4049589	ADME	AUC (0 to t) in Sprague-Dawley rat at 2.724 mg/kg, iv	Rattus norvegicus	1	ALA4049384	organism-based format	Scientific Literature
18.	ALA4049590	ADME	Cmax in Sprague-Dawley rat at 2.724 mg/kg, iv	Rattus norvegicus	1	ALA4049384	organism-based format	Scientific Literature
19.	ALA4049591	ADME	Tmax in Sprague-Dawley rat at 2.724 mg/kg, iv	Rattus norvegicus	1	ALA4049384	organism-based format	Scientific Literature
20.	ALA4049592	ADME	Half life in Sprague-Dawley rat at 2.724 mg/kg, iv	Rattus norvegicus	1	ALA4049384	organism-based format	Scientific Literature