# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4121728 | B | Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrate addition measured after 120 mins by fluorescence polarization assay | Homo sapiens | 62 | ALA4118126 | single protein format | Scientific Literature | |
2. | ALA4121729 | B | Inhibition of CAMKK2 in mouse N39 cells assessed as decrease in AMPKalpha phosphorylation at T172 preincubated for 80 mins followed by inomycin addition by ELISA | Mus musculus | 43 | ALA4118126 | cell-based format | Scientific Literature | |
3. | ALA4121730 | P | Solubility of the compound in pH 7.4 phosphate buffer saline after 1 hr by chemiluminescence nitrogen detection method | 58 | ALA4118126 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4827568 | B | Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity at 1 uM by [gamma-33P]-ATP assay relative to control | Homo sapiens | 32 | ALA4825714 | single protein format | Scientific Literature | |
5. | ALA4827569 | B | Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity at 0.1 uM by [gamma-33P]-ATP assay relative to control | Homo sapiens | 32 | ALA4825714 | single protein format | Scientific Literature | |
6. | ALA4827570 | B | Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity at 0.01 uM by [gamma-33P]-ATP assay relative to control | Homo sapiens | 32 | ALA4825714 | single protein format | Scientific Literature | |
7. | ALA4827571 | B | Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to control | Homo sapiens | 22 | ALA4825714 | single protein format | Scientific Literature | |
8. | ALA4827572 | B | Inhibition of wild-type human partial length CAMKK2 (D65 to V471 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 9 | ALA4825714 | assay format | Scientific Literature | |
9. | ALA4827573 | B | Inhibition of wild-type human partial length CAMKK1 (R65 to E414 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 9 | ALA4825714 | assay format | Scientific Literature | |
10. | ALA4827574 | B | Inhibition of wild-type human partial length CDK8 (M1 to T360 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 3 | ALA4825714 | assay format | Scientific Literature | |
11. | ALA4827575 | B | Inhibition of wild-type human partial length SGK (I60 to L431 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4825714 | assay format | Scientific Literature | |
12. | ALA4827576 | B | Inhibition of wild-type human partial length JAK3 JH1 catalytic domain (I781 to S1124 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 3 | ALA4825714 | assay format | Scientific Literature | |
13. | ALA4827577 | B | Inhibition of wild-type human partial length YSK4 (T1019 to H1328 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4825714 | assay format | Scientific Literature | |
14. | ALA4827578 | B | Inhibition of wild-type human partial length CDK11 (M1 to N360 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 3 | ALA4825714 | assay format | Scientific Literature | |
15. | ALA4827579 | B | Inhibition of wild-type human partial length CASK (M1 to H315 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4825714 | assay format | Scientific Literature | |
16. | ALA4827580 | B | Inhibition of wild-type human partial length ERK8 (M1 to P437 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4825714 | assay format | Scientific Literature | |
17. | ALA4827581 | B | Inhibition of wild-type human partial length CAMK2A (M1 to K328 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4825714 | assay format | Scientific Literature | |
18. | ALA4827582 | B | Inhibition of wild-type human partial length EPHB6 (Q634 to P948 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 3 | ALA4825714 | assay format | Scientific Literature | |
19. | ALA4827583 | B | Inhibition of wild-type human partial length SGK3 (M119 to L496 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4825714 | assay format | Scientific Literature | |
20. | ALA4827616 | B | Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assay | Homo sapiens | 19 | ALA4825714 | cell-based format | Scientific Literature |