# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4125280 | B | Inhibition of Candida albicans CYP51 assessed as reduction in [3-3H]lanosterol 14alpha-demethylation at 0.75 uM preincubated for 60 secs followed by NADPH addition measured after 60 mins by RP-HPLC analysis relative to control | Candida albicans | 17 | ALA4118269 | single protein format | Scientific Literature | |
2. | ALA4125281 | B | Inhibition of Aspergillus fumigatus CYP51 assessed as reduction in [3-3H]eburicol 14alpha-demethylation at 0.75 uM preincubated for 60 secs followed by NADPH addition measured after 60 mins by RP-HPLC analysis relative to control | Aspergillus fumigatus | 17 | ALA4118269 | assay format | Scientific Literature | |
3. | ALA4125282 | P | Lipophilicity, log P of the compound | 16 | ALA4118269 | small-molecule physicochemical format | Scientific Literature |