# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4124741 | Functional | Induction of methuosis in human MDA-MB-231 cells assessed as increase in vacuole formation at 1 uM after 24 hrs by phase contrast microscopic analysis relative to control | Homo sapiens | 23 | ALA4118249 | cell-based format | Scientific Literature | |
2. | ALA4124742 | Functional | Induction of methuosis in human MDA-MB-231 cells assessed as increase in vacuole formation at 10 uM after 24 hrs by phase contrast microscopic analysis relative to control | Homo sapiens | 23 | ALA4118249 | cell-based format | Scientific Literature | |
3. | ALA4124743 | Functional | Antiproliferative activity against human A375 cells after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
4. | ALA4124744 | Functional | Antiproliferative activity against human SK-MEL-28 cells after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
5. | ALA4124745 | Functional | Antiproliferative activity against human SK-MEL-30 cells after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
6. | ALA4124746 | Functional | Antiproliferative activity against human A549 cells after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
7. | ALA4124747 | Functional | Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
8. | ALA4124748 | Functional | Antiproliferative activity against human MDA-MB-435S cells after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
9. | ALA4124749 | Functional | Antiproliferative activity against human MCF7 cells after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
10. | ALA4124750 | Functional | Antiproliferative activity against human HCT116 cells after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
11. | ALA4124751 | Functional | Antiproliferative activity against human BGC823 cells after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
12. | ALA4124752 | Functional | Antiproliferative activity against human HepG2 cells after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
13. | ALA4124753 | ADME | Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 48 hrs by MTS assay | Homo sapiens | 2 | ALA4118249 | cell-based format | Scientific Literature | |
14. | ALA4124754 | Functional | Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by crystal violet staining based microscopic method | Homo sapiens | 1 | ALA4118249 | cell-based format | Scientific Literature | |
15. | ALA4124755 | Functional | Induction of methuosis in human MDA-MB-231 cells assessed as increase in vacuole formation at 2 uM after 12 to 24 hrs by optical microscopic analysis | Homo sapiens | 1 | ALA4118249 | cell-based format | Scientific Literature | |
16. | ALA4124756 | Functional | Induction of apoptosis in human MDA-MB-231 cells assessed as PARP cleavage at 0.5 to 4 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4118249 | cell-based format | Scientific Literature | |
17. | ALA4124757 | Functional | Induction of apoptosis in human MDA-MB-231 cells assessed as caspase-3 activation at 0.5 to 4 uM after 24 hrs | Homo sapiens | 1 | ALA4118249 | cell-based format | Scientific Literature | |
18. | ALA4124758 | Functional | Antiproliferative activity against human MDA-MB-231 cells at 2 uM after 48 hrs in presence of pan-caspase inhibitor Z-VAD-FMK by MTS assay | Homo sapiens | 1 | ALA4118249 | cell-based format | Scientific Literature | |
19. | ALA4124759 | Functional | Induction of methuosis in human MDA-MB-231 cells assessed as increase in vacuole formation at 2 uM after 24 hrs in presence of pan-caspase inhibitor Z-VAD-FMK by optical microscopic analysis | Homo sapiens | 1 | ALA4118249 | cell-based format | Scientific Literature | |
20. | ALA4124761 | Functional | Antiproliferative activity against human MDA-MB-231 cells at 2 uM after 48 hrs in presence of necrosis inhibitor necrostatin-1 by MTS assay | Homo sapiens | 1 | ALA4118249 | cell-based format | Scientific Literature |