# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4123982 | B | Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 mins | Dengue virus | 9 | ALA4118212 | single protein format | Scientific Literature | |
2. | ALA4123983 | A | Inhibition of human POLRMT using 5'-FAM labelled RNA primer/DNA template duplex assessed as single nucleotide incorporation rate at 500 uM after 5 mins by SDS-PAGE analysis relative to control | Homo sapiens | 9 | ALA4118212 | single protein format | Scientific Literature | |
3. | ALA4394392 | B | Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template measured after 2 hrs by microscintillation counting method | Hepatitis C virus | 13 | ALA4393666 | single protein format | Scientific Literature | |
4. | ALA4394393 | B | Inhibition of HCV NS5B RNA-dependent RNA polymerase assessed as chain termination of RNA synthesis by measuring reduction in UTP incorporation at 100 uM using 33P-labeled 5'-GG-3'/5'-AUGUAUAAUUAUUGUAGCC-3' as primer/template measured after 2 hrs by phosphor-screening analysis | Hepatitis C virus | 1 | ALA4393666 | single protein format | Scientific Literature | |
5. | ALA4394394 | A | Inhibition of human DNA polymerase-alpha assessed as reduction in [3H]dTTP incorporation in to activated calf thymus DNA substrate at 100 uM by scintillation counting method relative to control | Homo sapiens | 8 | ALA4393666 | single protein format | Scientific Literature | |
6. | ALA4394395 | B | Inhibition of HCV NS5B RNA-dependent RNA polymerase assessed as chain termination of RNA synthesis by measuring reduction in dUTP incorporation at 100 uM using 33P-labeled 5'-GG-3'/5'-AUGUAUAAUUAUUGUAGCC-3' as primer/template measured after 2 hrs by phosphor-screening analysis | Hepatitis C virus | 1 | ALA4393666 | single protein format | Scientific Literature | |
7. | ALA4394396 | A | Inhibition of human DNA polymerase-beta assessed as reduction in [3H]dTTP incorporation in to activated calf thymus DNA substrate at 100 uM by scintillation counting method relative to control | Homo sapiens | 8 | ALA4393666 | single protein format | Scientific Literature | |
8. | ALA4394397 | A | Inhibition of human DNA polymerase-gamma assessed as reduction in [3H]dTTP incorporation in to activated calf thymus DNA substrate at 100 uM by scintillation counting method relative to control | Homo sapiens | 8 | ALA4393666 | single protein format | Scientific Literature | |
9. | ALA4394398 | A | Inhibition of RNA polymerase 2 in human HeLa cell nuclear extract assessed as reduction in RNA transcription by PAGE analysis | Homo sapiens | 8 | ALA4393666 | cell-based format | Scientific Literature | |
10. | ALA4394399 | A | Inhibition of human mitochondrial DNA-dependent RNA polymerase activity at 100 uM using 33P-RNA/DNA primer/template by phosphor-imaging analysis | Homo sapiens | 4 | ALA4393666 | single protein format | Scientific Literature |