| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4121182 | B | Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by upregulation of CD69 and CD25 after 18 hrs | Homo sapiens | 7 | ALA4118107 | assay format | Scientific Literature | |
| 2. | ALA4121184 | B | Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cell-mediated lysis of human T24 cells preincubated for 4 hrs followed by compound washout measured after 18 hrs | Homo sapiens | 6 | ALA4118107 | assay format | Scientific Literature | |
| 3. | ALA4121188 | B | Binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cells by measuring levels of CD69 and CD25 at 0.1 uM after 18 hrs relative to control | Homo sapiens | 4 | ALA4118107 | assay format | Scientific Literature | |
| 4. | ALA4121189 | B | Potency index, ratio of zoledronate ED50 to test compound ED50 for binding affinity to butyrophilin 3A1 in human Vgamma9/Vdelta2 T-cells assessed as activation of Vgamma9/Vdelta2 T-cell-mediated lysis of human T24 cells | Homo sapiens | 4 | ALA4118107 | assay format | Scientific Literature | |
| 5. | ALA4121190 | F | Upregulation of CD69/CD25 levels in human CD8-positive T cells expressing alpha-beta TCR | Homo sapiens | 6 | ALA4118107 | cell-based format | Scientific Literature |
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