# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4124004 | Binding | Inhibition of MEK1/2 in EGF-stimulated human MDA-MB-231 cells assessed as reduction in pERK1/2 levels preincubated for 30 mins followed by EGF stimulation measured after 15 mins by Western blot analysis relative to control | Homo sapiens | 26 | ALA4118214 | cell-based format | Scientific Literature | |
2. | ALA4124005 | Binding | Inhibition of MEK5 in EGF-stimulated human MDA-MB-231 cells assessed as reduction in pERK5 levels preincubated for 30 mins followed by EGF stimulation measured after 15 mins by Western blot analysis relative to control | Homo sapiens | 26 | ALA4118214 | cell-based format | Scientific Literature | |
3. | ALA4124007 | ADME | Activation of MEK1/2 in EGF-stimulated human MDA-MB-231 cells assessed as increase in pERK1/2 levels preincubated for 30 mins followed by EGF stimulation measured after 15 mins by Western blot analysis relative to control | Homo sapiens | 3 | ALA4118214 | cell-based format | Scientific Literature |