# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4125121 | B | Inhibition of recombinant human C-terminal His10-tagged KLK7 (E23 to H252 residues) using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 19 | ALA4118260 | single protein format | Scientific Literature | |
2. | ALA4125122 | B | Inhibition of mouse KLK7 using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Mus musculus | 19 | ALA4118260 | single protein format | Scientific Literature | |
3. | ALA4125123 | B | Inhibition of mouse KLK7 at 30 uM using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay relative to control | Mus musculus | 8 | ALA4118260 | single protein format | Scientific Literature | |
4. | ALA4181447 | B | Inhibition of human trypsin preincubated for 10 mins followed by Boc-Gln-Ala-Arg-MCA peptide substrate addition measured after 30 mins by fluorescence analysis | Homo sapiens | 2 | ALA4177663 | protein format | Scientific Literature | |
5. | ALA4181448 | B | Inhibition of human chymotrypsin preincubated for 10 mins followed by Suc-Ala-Ala-Pro-Phe-MCA peptide substrate addition measured after 30 mins by fluorescence analysis | Homo sapiens | 2 | ALA4177663 | assay format | Scientific Literature | |
6. | ALA4181449 | B | Inhibition of thermolysin activated recombinant human C-terminal 10-His tagged KLK7 preincubated for 10 mins followed by MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 peptide substrate addition measured after 30 mins by fluorescence analysis | Homo sapiens | 15 | ALA4177663 | single protein format | Scientific Literature | |
7. | ALA4181450 | B | Inhibition of recombinant human C-terminal 10-His tagged KLK5 preincubated for 10 mins followed by Boc-Val-Pro-Arg-MCA peptide substrate addition measured after 30 mins by fluorescence analysis | Homo sapiens | 2 | ALA4177663 | single protein format | Scientific Literature | |
8. | ALA4181451 | B | Selectivity ratio of IC50 for human chymotrypsin to IC50 for recombinant human C-terminal 10-His tagged KLK7 | Homo sapiens | 2 | ALA4177663 | assay format | Scientific Literature | |
9. | ALA4222616 | B | Inhibition of recombinant human KLK7 using MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 22 | ALA4219155 | single protein format | Scientific Literature |