| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4124009 | B | Inhibition of recombinant CYP17 (unknown origin) expressed in human AD293 cells using [21-3H]17alpha-hydroxypregnenolone as substrate preincubated for 60 mins followed by substrate addition measured after 4 hrs Topcount method | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 2. | ALA4124010 | B | Inhibition of CYP19 (unknown origin) by Becton Dickinson aromatase assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 3. | ALA4124011 | A | Inhibition of human CYP3A4 using testosterone as substrate by LC-MS/MS analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA4124012 | B | Selectivity index, ratio of IC50 for human CYP3A4 to IC50 for recombinant CYP17 (unknown origin) | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 5. | ALA4124013 | B | Selectivity index, ratio of IC50 for CYP19 (unknown origin) to IC50 for recombinant CYP17 (unknown origin) | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 6. | ALA4124014 | A | Half-life in guinea pig liver microsomes in presence of NADPH regenerating system by LC/MS/MS method | Cavia porcellus | 4 | microsome format | Scientific Literature | ||
| 7. | ALA4124015 | A | Cmax in guinea pig at 1 mg/kg, iv by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA4124016 | A | Tmax in guinea pig at 1 mg/kg, iv by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA4124017 | A | Half-life in guinea pig at 1 mg/kg, iv by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA4124018 | A | Volume of distribution in guinea pig at 1 mg/kg, iv by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA4124019 | A | Clearance in guinea pig at 1 mg/kg, iv by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA4124020 | A | AUC (0 to infinity) in guinea pig at 1 mg/kg, iv by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA4124021 | A | Cmax in guinea pig at 10 mg/kg, po by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA4124022 | A | Tmax in guinea pig at 10 mg/kg, po by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 15. | ALA4124023 | A | Half-life in guinea pig at 10 mg/kg, po by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA4124024 | A | AUC (0 to infinity) in guinea pig at 10 mg/kg, po by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 17. | ALA4124025 | A | Oral bioavailability in guinea pig at 10 mg/kg by LC-MS/MS analysis | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
| 18. | ALA4257176 | B | Inhibition of recombinant CYP17 (unknown origin) expressed in human AD293 cells using 21[3H]-17alpha-hydroxyl-pregnenolone as substrate pretreated for 60 mins followed by substrate addition and measured after 4 hrs by Topcount method | Homo sapiens | 64 | cell-based format | Patent Bioactivity Data | ||
| 19. | ALA4257177 | B | Inhibition of recombinant CYP11B1 (unknown origin) expressed in human AD293 cells using 11-deoxycortisol as substrate pretreated for 60 mins followed by substrate addition and measured after 12 hrs by LC/MS analysis | Homo sapiens | 60 | cell-based format | Patent Bioactivity Data | ||
| 20. | ALA4257178 | B | Inhibition of recombinant CYP21 (unknown origin) expressed in human AD293 cells using 17alpha-hydroxyprogesterone as substrate pretreated for 60 mins followed by substrate addition and measured after 45 mins by LC/MS analysis | Homo sapiens | 62 | cell-based format | Patent Bioactivity Data |
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