# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4122262 | B | Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Boc-QRR-AMC as substrate after 15 mins by automated fluorescence assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
2. | ALA4122263 | B | Inhibition of recombinant C-terminal His10-tagged human uPA (M1 to L431 residues) expressed in mouse NS0 cells using Z-GGR-AMC as substrate after 15 mins by automated fluorescence assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
3. | ALA4122265 | B | Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Boc-QRR-AMC as substrate after 15 mins by manual fluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
4. | ALA4122266 | B | Inhibition of recombinant C-terminal His10-tagged human uPA (M1 to L431 residues) expressed in mouse NS0 cells using Z-GGR-AMC as substrate after 15 mins by manual fluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
5. | ALA4122267 | B | Selectivity ratio of IC50 for recombinant C-terminal His10-tagged human uPA (M1 to L431 residues) to IC50 for recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant by manual fluorescence assay | Homo sapiens | 7 | assay format | Scientific Literature |