| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4121934 | B | Inhibition of His6-tagged human wild-type PTP1B catalytic domain at 2000 nM using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA4121935 | B | Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant at 250 nM using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 3. | ALA4121936 | B | Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4121937 | B | Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant at 2000 nM using pNPP as substrate incubated for 10 to 40 mins by quenched phosphatase activity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4121938 | B | Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant at 2000 nM using pNPP as substrate incubated for = | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4121939 | B | Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant at 500 nM using DADEpYLIPQQG as substrate incubated for 90 mins by continuous phosphatase activity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4121940 | B | Inhibition of His6-tagged human wild-type PTP1B catalytic domain at 500 nM using DADEpYLIPQQG as substrate incubated for 90 mins by continuous phosphatase activity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4121941 | B | Inhibition of His6-tagged human wild-type PTP1B catalytic domain overexpressed in Escherichia coli crude cell lysate using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA4121942 | B | Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant overexpressed in Escherichia coli crude cell lysate using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA4121943 | B | Inhibition of His6-tagged human wild-type PTP1B catalytic domain overexpressed in Escherichia coli BL21(DE3) cells at 100 uM using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4121944 | B | Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant overexpressed in Escherichia coli BL21(DE3) cells using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4121945 | B | Binding affinity to His6-tagged human wild-type PTP1B catalytic domain overexpressed in Escherichia coli crude cell lysate at 6.66 uM incubated for 90 mins by SDS-PAGE and LC-MS/MS method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4121946 | B | Binding affinity to allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant overexpressed in Escherichia coli crude cell lysate incubated for 90 mins by SDS-PAGE and LC-MS/MS method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA4121947 | B | Binding affinity to His6-tagged human wild-type PTP1B catalytic domain overexpressed in Escherichia coli BL21(DE3) cells at 100 uM using pNPP as substrate after 90 mins by SDS-PAGE analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4121948 | B | Binding affinity to allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant overexpressed in Escherichia coli BL21(DE3) cells at 25 to 100 uM after 90 mins by SDS-PAGE and LC-MS/MS method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4121949 | B | Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP catalytic domain at 500 nM using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 17. | ALA4121950 | B | Inhibition of His6-tagged human wild-type PTP catalytic domain at 500 nM using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 18. | ALA4121961 | B | Inhibition of allosterically sensitized mutant form of His6-tagged human SHP1 catalytic domain at 500 nM using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 19. | ALA4121962 | B | Inhibition of allosterically sensitized mutant form of His6-tagged human SHP2 catalytic domain at 500 nM at 500 nM using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 20. | ALA4121963 | B | Inhibition of allosterically sensitized mutant form of His6-tagged human FAP1 catalytic domain at 500 nM using pNPP as substrate incubated for 90 mins by quenched phosphatase activity assay | Homo sapiens | 4 | single protein format | Scientific Literature |
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