| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4125121 | B | Inhibition of recombinant human C-terminal His10-tagged KLK7 (E23 to H252 residues) using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 19 | ALA4118260 | single protein format | Scientific Literature | |
| 2. | ALA4125122 | B | Inhibition of mouse KLK7 using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Mus musculus | 19 | ALA4118260 | single protein format | Scientific Literature | |
| 3. | ALA4125123 | B | Inhibition of mouse KLK7 at 30 uM using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay relative to control | Mus musculus | 8 | ALA4118260 | single protein format | Scientific Literature | |
| 4. | ALA4222616 | B | Inhibition of recombinant human KLK7 using MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 22 | ALA4219155 | single protein format | Scientific Literature | |
| 5. | ALA4222617 | B | Inhibition of recombinant human KLK5 using Boc-Val-Pro-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 3 | ALA4219155 | single protein format | Scientific Literature | |
| 6. | ALA4222618 | B | Inhibition of human chymotrypsin using Suc-Ala-Ala-Pro-Phe-MCA as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 3 | ALA4219155 | assay format | Scientific Literature | |
| 7. | ALA4222619 | B | Inhibition of human trypsin using Boc-Gln-Ala-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 3 | ALA4219155 | protein format | Scientific Literature | |
| 8. | ALA4222620 | B | Inhibition of human chymotrypsin at 30 uM using Suc-Ala-Ala-Pro-Phe-MCA as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 1 | ALA4219155 | assay format | Scientific Literature | |
| 9. | ALA4222621 | B | Selectivity index, ratio of IC50 for recombinant human KLK5 to IC50 for recombinant human KLK7 | Homo sapiens | 3 | ALA4219155 | assay format | Scientific Literature | |
| 10. | ALA4222622 | B | Selectivity index, ratio of IC50 for human chymotrypsin to IC50 for recombinant human KLK7 | Homo sapiens | 3 | ALA4219155 | assay format | Scientific Literature | |
| 11. | ALA4222623 | B | Selectivity index, ratio of IC50 for human trypsin to IC50 for recombinant human KLK7 | Homo sapiens | 3 | ALA4219155 | assay format | Scientific Literature |
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