#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4145211	Binding	Binding affinity to PARP1 in human OVCAR8 cells assessed as reduction in [125I]-KX1 binding by gamma counting analysis	Homo sapiens	35	ALA4138313	cell-based format	Scientific Literature
2.	ALA4145213	Binding	Inhibition of PARP1 in human OVCAR8 cells assessed as reduction in PAR expression at 1 to 10000 nM after 6 hrs by Western blot analysis	Homo sapiens	3	ALA4138313	cell-based format	Scientific Literature
3.	ALA4145215	ADME	Induction of DNA double strand breaks in human OVCAR8 cells assessed as increase in gamma-H2AX expression after 24 hrs by DAPI-based fluorescence microscopy	Homo sapiens	1	ALA4138313	cell-based format	Scientific Literature
4.	ALA4145217	ADME	Cytotoxicity against mouse wild type MEF cells assessed as reduction in cell viability after 4 to 7 days by cell-titer glo assay	Mus musculus	24	ALA4138313	cell-based format	Scientific Literature
5.	ALA4145218	ADME	Cytotoxicity against mouse PARP1 deficient MEF cells assessed as reduction in cell viability after 4 to 7 days by cell-titer glo assay	Mus musculus	9	ALA4138313	cell-based format	Scientific Literature
6.	ALA4145220	ADME	Cytotoxicity against mouse PARP2 deficient MEF cells expressing PARP1 assessed as reduction in cell viability after 4 to 7 days by cell-titer glo assay	Mus musculus	31	ALA4138313	cell-based format	Scientific Literature
7.	ALA4145222	ADME	Cytotoxicity against human BRCA1-restored UWB1.289 cells assessed as reduction in cell viability after 4 to 7 days by cell-titer glo assay	Homo sapiens	5	ALA4138313	cell-based format	Scientific Literature
8.	ALA4145223	ADME	Cytotoxicity against human BRCA1-deficient UWB1.289 cells assessed as reduction in cell viability after 4 to 7 days by cell-titer glo assay	Homo sapiens	5	ALA4138313	cell-based format	Scientific Literature
9.	ALA4145224	Binding	Inhibition of human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected sf9 cells using histone as substrate after 1 hr by streptavidin-horseradish peroxidase-based luminescence assay	Homo sapiens	4	ALA4138313	cell-based format	Scientific Literature
10.	ALA4145225	Binding	Inhibition of human N-terminal GST-tagged TNKS2 (667 to 1166 residues) expressed in baculovirus infected sf9 cells using histone as substrate after 1 hr by streptavidin-horseradish peroxidase-based luminescence assay	Homo sapiens	4	ALA4138313	cell-based format	Scientific Literature
11.	ALA4145226	ADME	Safety index, ratio compound EC50 to olaparib EC50 for BRCA1 deficient human UWB1.289 cells	Homo sapiens	4	ALA4138313	assay format	Scientific Literature
12.	ALA4145228	Binding	Inhibition of human N-terminal GST-tagged TNKS2 (667 to 1166 residues) expressed in baculovirus infected sf9 cells at 10 uM using histone as substrate after 1 hr by streptavidin-horseradish peroxidase-based luminescence assay	Homo sapiens	3	ALA4138313	cell-based format	Scientific Literature