# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4151400 | Functional | Agonist activity at mouse MC1R expressed in HEK293 cells incubated for 2 hrs by AlphaScreen cAMP assay | Mus musculus | 15 | ALA4145669 | cell-based format | Scientific Literature | |
2. | ALA4151401 | Functional | Agonist activity at mouse MC1R expressed in HEK293 cells incubated for 2 hrs by AlphaScreen cAMP assay relative to NDP-MSH | Mus musculus | 3 | ALA4145669 | cell-based format | Scientific Literature | |
3. | ALA4151404 | Functional | Inverse agonist activity at mouse MC5R expressed in HEK293 cells at 100 uM incubated for 2 hrs by AlphaScreen cAMP assay | Mus musculus | 18 | ALA4145669 | cell-based format | Scientific Literature | |
4. | ALA4151405 | Functional | Agonist activity at mouse MC3R expressed in HEK293 cells at 100 uM incubated for 2 hrs by AlphaScreen cAMP assay relative to untreated control | Mus musculus | 19 | ALA4145669 | cell-based format | Scientific Literature | |
5. | ALA4151406 | Functional | Agonist activity at mouse MC4R expressed in HEK293 cells at 100 uM incubated for 2 hrs by AlphaScreen cAMP assay relative to untreated control | Mus musculus | 19 | ALA4145669 | cell-based format | Scientific Literature | |
6. | ALA4151407 | Functional | Antagonist activity at mouse MC3R expressed in HEK293 cells assessed as reduction in NDP-MSH-induced response incubated for 2 hrs by AlphaScreen cAMP assay based Schild analysis | Mus musculus | 19 | ALA4145669 | cell-based format | Scientific Literature | |
7. | ALA4151408 | Functional | Antagonist activity at mouse MC4R expressed in HEK293 cells assessed as reduction in NDP-MSH-induced response incubated for 2 hrs by AlphaScreen cAMP assay based Schild analysis | Mus musculus | 20 | ALA4145669 | cell-based format | Scientific Literature | |
8. | ALA4151409 | Binding | Selectivity index, ratio of pA2 for antagonist activity at mouse MC3R expressed in HEK293 cells to pA2 for antagonist activity at mouse MC4R expressed in HEK293 cells | Mus musculus | 18 | ALA4145669 | cell-based format | Scientific Literature |