# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4144007 | F | Antagonist activity at recombinant human LPA1 expressed in CHO cells assessed as reduction in LPA-induced intracellular calcium level pretreated followed by LPA addition by Fura-2-AM dye based fluorescence assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
2. | ALA4144010 | F | Inhibition of LPA-induced increase of intraurethral pressure in po dosed rat measured after 1 hr | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
3. | ALA4144011 | F | Antagonist activity at LPA1 in CD(SD)IGS rat urethra assessed as inhibition of LPA-induced urethra contraction at 1 uM pretreated for 30 mins followed by LPA addition | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
4. | ALA4144012 | F | Antagonist activity at LPA1 in CD(SD)IGS rat urethra assessed as inhibition of LPA-induced urethra contraction at 1 uM pretreated for 30 mins prior to LPA addition followed by compound washout every 10 minutes for 2 times and subsequent LPA stimulation | Rattus norvegicus | 2 | assay format | Scientific Literature |