# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4142317 | B | Inhibition of human Lig1 at 10 uM using double strand nicked DNA as substrate after 30 mins in presence of ATP by acrylamide-based fluorescence-assay | Homo sapiens | 13 | ALA4138186 | single protein format | Scientific Literature | |
2. | ALA4142318 | F | Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay | Homo sapiens | 1 | ALA4138186 | cell-based format | Scientific Literature | |
3. | ALA4142319 | F | Antiproliferative activity against human DLD1 cells after 48 hrs by MTT assay | Homo sapiens | 1 | ALA4138186 | cell-based format | Scientific Literature | |
4. | ALA4142320 | F | Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay | Homo sapiens | 1 | ALA4138186 | cell-based format | Scientific Literature | |
5. | ALA4142321 | F | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay | Homo sapiens | 1 | ALA4138186 | cell-based format | Scientific Literature | |
6. | ALA4142322 | F | Antiproliferative activity against human 4TI cells after 48 hrs by MTT assay | Homo sapiens | 1 | ALA4138186 | cell-based format | Scientific Literature | |
7. | ALA4142323 | A | Cytotoxicity against HEK293 cells after 48 hrs by MTT assay | Homo sapiens | 1 | ALA4138186 | cell-based format | Scientific Literature | |
8. | ALA4142324 | F | Antiproliferative activity against human MDA-MB-231 cells at 10 uM after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4138186 | cell-based format | Scientific Literature | |
9. | ALA4142325 | F | Antiproliferative activity against human HeLa cells at 10 uM after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4138186 | cell-based format | Scientific Literature | |
10. | ALA4142326 | F | Antiproliferative activity against human DLD1 cells at 10 uM after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4138186 | cell-based format | Scientific Literature | |
11. | ALA4142327 | F | Antiproliferative activity against human HepG2 cells at 10 uM after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4138186 | cell-based format | Scientific Literature | |
12. | ALA4142328 | F | Antiproliferative activity against human 4TI cells at 10 uM after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4138186 | cell-based format | Scientific Literature | |
13. | ALA4142329 | B | Inhibition of human Lig3beta at 10 uM using double strand nicked DNA as substrate at 3.125 to 50 uM after 30 mins in presence of ATP by acrylamide-based fluorescence-assay | Homo sapiens | 1 | ALA4138186 | single protein format | Scientific Literature | |
14. | ALA4142330 | B | Inhibition of human DNA Lig4/XRCCR at 10 uM using double strand nicked DNA as substrate after 30 mins in presence of ATP by acrylamide-based fluorescence-assay | Homo sapiens | 1 | ALA4138186 | protein complex format | Scientific Literature | |
15. | ALA4142331 | B | Inhibition of T4 DNA ligase at 10 uM using double strand nicked DNA as substrate at 3.125 to 50 uM after 30 mins in presence of ATP by acrylamide-based fluorescence-assay | Tequatrovirus T4 | 1 | ALA4138186 | single protein format | Scientific Literature | |
16. | ALA4142332 | B | Competitive inhibition of human Lig1 using non-ligatable double stranded nicked DNA as substrate after 2 hrs in presence of ATP by EMSA | Homo sapiens | 1 | ALA4138186 | single protein format | Scientific Literature | |
17. | ALA4142333 | B | Binding affinity to Escherichia coli pUC18 DNA assessed as protection against DNase1-mediated cleavage at 250 to 700 uM preincubated for 30 mins followed by DNase1 addition measured after 5 mins by 1% agarose gel based UV-transilluminator analysis | Escherichia coli | 1 | ALA4138186 | nucleic acid format | Scientific Literature | |
18. | ALA4142335 | F | Induction of apoptosis in human DLD1 cells assessed as cell shrinkage by bright field microscopy | Homo sapiens | 1 | ALA4138186 | cell-based format | Scientific Literature | |
19. | ALA4142336 | F | Induction of apoptosis in human DLD1 cells assessed as cell detachment from culture surface by bright field microscopy | Homo sapiens | 1 | ALA4138186 | cell-based format | Scientific Literature | |
20. | ALA4142337 | F | Anti-migratory activity in human DLD1 cells at 2.5 to 5 uM after 12 to 48 hrs by wound healing assay | Homo sapiens | 1 | ALA4138186 | cell-based format | Scientific Literature |