# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4146160 | F | Antimycobacterial activity against Mycobacterium bovis BCG at 25 uM after 10 days by broth dilution method relative to control | Mycobacterium tuberculosis | 14 | ALA4145451 | organism-based format | Scientific Literature | |
2. | ALA4146161 | F | Antimycobacterial activity against Mycobacterium bovis BCG after 10 days by broth dilution method | Mycobacterium tuberculosis | 14 | ALA4145451 | organism-based format | Scientific Literature | |
3. | ALA4146166 | B | Inhibition of Mycobacterium tuberculosis His-tagged DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs over 6 mins by spectrophotometric method | Mycobacterium tuberculosis | 5 | ALA4145451 | single protein format | Scientific Literature | |
4. | ALA4146167 | B | Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using DHF as substrate measured every 30 secs over 6 mins by spectrophotometric method | Homo sapiens | 5 | ALA4145451 | single protein format | Scientific Literature | |
5. | ALA4146168 | B | Selectivity index, ratio of IC50 for inhibition of recombinant human DHFR to IC50 for inhibition of Mycobacterium tuberculosis His-tagged DHFR | 4 | ALA4145451 | assay format | Scientific Literature |