# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4151994 | B | Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes pre-incubated for 1 hr by FRET-based binding assay | Homo sapiens | 47 | ALA4145692 | cell-based format | Scientific Literature | |
2. | ALA4151997 | P | Kinetic solubility in pH 7.4 HEPES-BSA buffer at 5 uM incubated for 24 hrs at 20 degC by HPLC method | 57 | ALA4145692 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4152001 | P | Thermodynamic solubility in pH 7.4 PBS buffer incubated for 24 hrs at 22 degC by HPLC method | 7 | ALA4145692 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4152002 | P | Thermodynamic solubility in pH 7.4 PBS/Cdx buffer incubated for 24 hrs at 22 degC by HPLC method | 7 | ALA4145692 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4152003 | P | Chemical stability in pH 7.4 PBS buffer assessed as parent compound remaining at 10 uM incubated for 24 hrs by RP-HPLC method | 7 | ALA4145692 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4152004 | P | Chemical stability in pH 7.4 PBS/Cdx buffer assessed as parent compound remaining at 10 uM incubated for 24 hrs by RP-HPLC method | 7 | ALA4145692 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4152005 | F | Inhibition of eosinophil infiltration in Balb/c mouse model of 8 day model of of allergic eosinophilic airway inflammation at 300 nmol/kg dosed intranasally 2 hrs before ovalbumin challenge by hemocytometry | Mus musculus | 7 | ALA4145692 | organism-based format | Scientific Literature |