| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4147757 | B | Inhibition of FITC-BAK binding to His6 tagged MBP fused recombinant human MCL1 (172 to 327 residues) expressed in Escherichia coli by fluorescence polarization competition assay | Homo sapiens | 1 | ALA4145520 | assay format | Scientific Literature | |
| 2. | ALA4147758 | F | Growth inhibition of human A375 cells after 48 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA4145520 | cell-based format | Scientific Literature | |
| 3. | ALA5113870 | B | Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assay | Homo sapiens | 8 | ALA5113375 | protein complex format | Scientific Literature | |
| 4. | ALA5232900 | B | Binding affinity to BCL-xL (unknown origin) assessed as inhibition constant | Homo sapiens | 13 | ALA5230167 | single protein format | Scientific Literature | |
| 5. | ALA5232902 | B | Inhibition of FITC-labelled BAK BH3 peptide to MCL-1 (172 to 327 residues) (unknown origin) assessed as inhibition constant by fluorescence polarization competition assay | Homo sapiens | 1 | ALA5230167 | single protein format | Scientific Literature | |
| 6. | ALA5232904 | B | Selectivity index, ratio of Ki for inhibition of FITC-labelled BAK BH3 peptide to MCL-1 (172 to 327 residues) (unknown origin) assessed as inhibition constant to Ki for binding affinity to BCL-xL (unknown origin) assessed as inhibition constant | Homo sapiens | 1 | ALA5230167 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!