| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4150877 | B | Inhibition of B-Raf (unknown origin) at 10 uM using inactive MEK as substrate pretreated for 20 mins followed by substrate addition and measured after 30 mins in presence of [gamma32P]ATP by autoradiography | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 2. | ALA4150878 | B | Inhibition of C-Raf (unknown origin) at 10 uM using inactive MEK as substrate pretreated for 20 mins followed by substrate addition and measured after 30 mins in presence of [gamma32P]ATP by autoradiography | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 3. | ALA4150879 | B | Inhibition of wild-type MEK1 (unknown origin) at 10 uM using inactive ERK2 as substrate pretreated for 20 mins followed by substrate addition and measured after 30 mins in presence of [gamma32P]ATP by autoradiography | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 4. | ALA4150880 | B | Inhibition of ERK (unknown origin) | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 5. | ALA4150881 | F | Down regulation of total B-Raf level in human COLO205 cells harboring B-Raf V600E mutant by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4150882 | F | Down regulation of total C-Raf level in human COLO205 cells harboring B-Raf V600E mutant by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4150883 | F | Down regulation of total MEK level in human COLO205 cells harboring B-Raf V600E mutant by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4150884 | F | Down regulation of total ERK level in human COLO205 cells harboring B-Raf V600E mutant at 1 to 10 uM measured after 18 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4150889 | B | Increase in MEK phosphorylation in human COLO205 cells harboring B-Raf V600E mutant at 1 uM after 18 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4150890 | B | Increase in ERK phosphorylation in human COLO205 cells harboring B-Raf V600E mutant at 1 uM after 18 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!