# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA638176 | Physicochemical | Partition coefficient (logP) | 15 | ALA1134299 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA830350 | Binding | Binding affinity for protein kinase C-alpha C1a and C1b domains | 4 | ALA1138760 | assay format | Scientific Literature | ||
3. | ALA876368 | Binding | Binding affinity for isolated C1b domain of protein kinase C-delta | 4 | ALA1138760 | single protein format | Scientific Literature | ||
4. | ALA872399 | Binding | Inhibition of [3H]PDBu binding to recombinant protein kinase C alpha was determined at pH 7.4, 37 degree C for 5 min | Homo sapiens | 7 | ALA1141072 | single protein format | Scientific Literature | |
5. | ALA872291 | Binding | Inhibition of [3H]-PDBu binding to C1b domain of protein kinase C delta without phosphatidylserine | Homo sapiens | 5 | ALA1141072 | single protein format | Scientific Literature | |
6. | ALA871845 | Binding | Inhibition of [3H]PDBu binding to C1b domain of protein kinase C delta with phosphatidylserine | Homo sapiens | 6 | ALA1141072 | single protein format | Scientific Literature | |
7. | ALA860607 | Binding | Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserine | Homo sapiens | 21 | ALA1139005 | single protein format | Scientific Literature | |
8. | ALA860617 | Functional | Activation of alpha secretase assessed by sAPPalpha secretion in W4 cells relative to control | Mus musculus | 10 | ALA1139005 | cell-based format | Scientific Literature | |
9. | ALA3396875 | Binding | Displacement of [20-3H] phorbol 12, 13-dibutylate from recombinant PKCalpha (unknown origin) in presence of 100 ug/ml 100% phosphatidylserine | Homo sapiens | 22 | ALA3392971 | single protein format | Scientific Literature | |
10. | ALA3396876 | Binding | Displacement of [20-3H] phorbol 12, 13-dibutylate from recombinant PKCepsilon (unknown origin) in presence of 100 ug/ml 100% phosphatidylserine | Homo sapiens | 22 | ALA3392971 | single protein format | Scientific Literature | |
11. | ALA3396877 | Binding | Selectivity index, ratio of Ki for recombinant PKCalpha (unknown origin) in presence of 100 ug/ml 100% phosphatidylserine to Ki for recombinant PKCepsilon (unknown origin) in presence of 100 ug/ml 100% phosphatidylserine | Homo sapiens | 21 | ALA3392971 | assay format | Scientific Literature | |
12. | ALA3396878 | Physicochemical | Lipophilicity, log P of the compound | 21 | ALA3392971 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA3394956 | Binding | Displacement of [20-3H] phorbol 12, 13-dibutylate from recombinant PKCalpha (unknown origin) in presence of nuclear membrane mimetic lipid mixture | Homo sapiens | 22 | ALA3392971 | cell membrane format | Scientific Literature | |
14. | ALA3394957 | Binding | Displacement of [20-3H] phorbol 12, 13-dibutylate from recombinant PKCepsilon (unknown origin) in presence of nuclear membrane mimetic lipid mixture | Homo sapiens | 22 | ALA3392971 | cell membrane format | Scientific Literature | |
15. | ALA3394958 | Binding | Selectivity index, ratio of Ki for recombinant PKCalpha (unknown origin) in presence of nuclear membrane mimetic lipid mixture to Ki for recombinant PKCepsilon (unknown origin) in presence of nuclear membrane mimetic lipid mixture | Homo sapiens | 21 | ALA3392971 | cell membrane format | Scientific Literature | |
16. | ALA760366 | Binding | Displacement of [20-3H]-PDBU ligand from recombinant protein kinase C (baculovirus) | 15 | ALA1134299 | single protein format | Scientific Literature | ||
17. | ALA769622 | Binding | Binding affinity for Protein kinase C alpha C1a or C1b domain | 4 | ALA1145817 | single protein format | Scientific Literature | ||
18. | ALA5031250 | Binding | Displacement of [3H]-PDBu from recombinant human PKCalpha by scintillation counter method | Homo sapiens | 2 | ALA5030521 | single protein format | Scientific Literature | |
19. | ALA5031251 | Binding | Displacement of [3H]-PDBu from recombinant human PKCepsilon by scintillation counter method | Homo sapiens | 5 | ALA5030521 | single protein format | Scientific Literature | |
20. | ALA5031254 | Binding | Activation of GFP-fused PKCepsilon in HeLa cells assessed as translocation of PKCepsilon from cytosol to membrane measured after 30 mins by DAPI staining based fluorescence microscopy | Homo sapiens | 6 | ALA5030521 | subcellular format | Scientific Literature |