# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4134360 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess assay | Mus musculus | 21 | cell-based format | Scientific Literature | ||
2. | ALA4134361 | A | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 50 uM after 24 hrs by MTT assay | Mus musculus | 20 | cell-based format | Scientific Literature | ||
3. | ALA4820717 | F | Down regulation of PCSK9 mRNA expression in human HepG2 cells at 50 uM incubated for 24 hrs by SYBR green dye-based qRT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA4820718 | F | Down regulation of PCSK9 mRNA expression in human HepG2 cells incubated for 24 hrs by SYBR green dye-based qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA4820719 | F | Down regulation of PCSK9 protein expression in human HepG2 cells at 10 to 50 uM incubated for 24 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA4820720 | F | Up regulation of LDLR protein expression in human HepG2 cells at 10 to 50 uM incubated for 24 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4820721 | B | Inhibition of PCSK9 (unknown origin) interaction with LDLR (unknown origin) by ELISA | Homo sapiens | 19 | protein format | Scientific Literature |