| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4134762 | F | Stimulation of glucose consumption in rat L6 cells at 20 uM incubated for 12 hrs by glucose assay reagent based glucose oxidase method relative to untreated control | Rattus norvegicus | 42 | cell-based format | Scientific Literature | ||
| 2. | ALA4134764 | F | Inhibition of glucose production in Sprague-Dawley rat primary hepatocytes grown under gluconeogenic medium assessed as glucose production level at 5 uM incubated for 6 hrs by glucose assay reagent based glucose oxidase method (Rvb = 100%) | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA4134765 | F | Inhibition of glucose production in Sprague-Dawley rat primary hepatocytes grown under gluconeogenic medium assessed as glucose production level at 10 uM incubated for 6 hrs by glucose assay reagent based glucose oxidase method (Rvb = 100%) | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
| 4. | ALA4134766 | F | Inhibition of glucose production in Sprague-Dawley rat primary hepatocytes grown under gluconeogenic medium assessed as glucose production level at 20 uM incubated for 6 hrs by glucose assay reagent based glucose oxidase method (Rvb = 100%) | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA4134767 | F | Inhibition of glucose production in Sprague-Dawley rat primary hepatocytes grown under gluconeogenic medium incubated for 6 hrs by glucose assay reagent based glucose oxidase method (Rvb = 100%) | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA4134769 | B | Activation of AMPKalpha in rat L6 cells assessed as increase in AMPKalpha Thr172 phosphorylation incubated for 1 hrs by Western blot method | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 7. | ALA4134770 | B | Activation of AMPKalpha in rat L6 cells assessed as increase in ACC phosphorylation incubated for 1 hrs by Western blot method | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 8. | ALA4134771 | B | Activation of human recombinant AMPKalpha1beta1gamma1 expressed in Escherichia coli at 20 uM incubated for 1 hr using serine/threonine kinase substrate | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 9. | ALA4134772 | B | Activation of human recombinant AMPKalpha1beta1gamma2 expressed in Escherichia coli at 20 uM incubated for 1 hr using serine/threonine kinase substrate | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 10. | ALA4134773 | B | Activation of human recombinant AMPKalpha1beta2gamma1 expressed in Escherichia coli at 20 uM incubated for 1 hr using serine/threonine kinase substrate | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 11. | ALA4134774 | B | Activation of human recombinant AMPKalpha1beta2gamma3 expressed in Escherichia coli at 20 uM incubated for 1 hr using serine/threonine kinase substrate | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 12. | ALA4134775 | B | Activation of human recombinant AMPKalpha2beta1gamma1 expressed in Escherichia coli at 20 uM incubated for 1 hr using serine/threonine kinase substrate | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 13. | ALA4134776 | B | Activation of human recombinant AMPKalpha2beta1gamma3 expressed in Escherichia coli at 20 uM incubated for 1 hr using serine/threonine kinase substrate | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 14. | ALA4134777 | B | Activation of human recombinant AMPKalpha2beta2gamma1 expressed in Escherichia coli at 20 uM incubated for 1 hr using serine/threonine kinase substrate | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 15. | ALA4134778 | B | Activation of human recombinant AMPKalpha2beta2gamma2 expressed in Escherichia coli at 20 uM incubated for 1 hr using serine/threonine kinase substrate | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 16. | ALA4134795 | F | Inhibition of mitochondrial membranes potential in rat L6 cells assessed as mitochondrial membranes potential level at 20 uM incubated for 40 mins by JC1 dye staining based fluorescence assay (Rvb = 100 +/- 2.8%) | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
| 17. | ALA4134796 | F | Inhibition of oxygen consumption rate in rat L6 cells assessed as oxygen consumption level at 10 uM (Rvb = 100 +/- 1.6%) | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA4134797 | F | Inhibition of oxygen consumption rate in rat L6 cells assessed as oxygen consumption level at 20 uM (Rvb = 100 +/- 1.6%) | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 19. | ALA4134798 | F | Inhibition of oxygen consumption rate in isolated mitochondria from rat L6 cells assessed as oxygen consumption level at 1.2 uM (Rvb = 100 +/- 1.9%) | Rattus norvegicus | 4 | mitochondrion format | Scientific Literature | ||
| 20. | ALA4134799 | F | Inhibition of oxygen consumption rate in isolated mitochondria from rat L6 cells assessed as oxygen consumption level at 2.5 uM (Rvb = 100 +/- 1.9%) | Rattus norvegicus | 4 | mitochondrion format | Scientific Literature |
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