#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4133145	B	Antagonist activity at human P2X7 receptor expressed in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake at 10 uM after 30 mins by FLIPR assay relative to 1 mM ATP	Homo sapiens	51	ALA4130413	assay format	Scientific Literature
2.	ALA4133146	T	Toxicity in Swiss mouse peritoneal macrophages assessed as LDH release at 10 uM after 60 mins relative to 0.05% Triton X-100	Mus musculus	51	ALA4130413	cell-based format	Scientific Literature
3.	ALA4133147	B	Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake at 10 uM preincubated for 10 mins followed by ATP addition measured after 20 mins by FLIPR assay relative to 1 mM ATP	Homo sapiens	51	ALA4130413	cell-based format	Scientific Literature
4.	ALA4133148	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake after 25 mins by flow cytometric analysis	Mus musculus	8	ALA4130413	single protein format	Scientific Literature
5.	ALA4133149	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced current at holding potential of -60 mV preincubated for 5 mins followed by ATP addition measured after 5 mins by Whole cell patch-clamp analysis	Mus musculus	8	ALA4130413	single protein format	Scientific Literature
6.	ALA4133150	A	Cytotoxicity against Swiss mouse peritoneal macrophages after 24 hrs by LDH-release assay	Mus musculus	7	ALA4130413	cell-based format	Scientific Literature
7.	ALA4133151	B	Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10 mins followed by ATP addition measured after 20 mins by spectrofluorometric analysis	Homo sapiens	9	ALA4130413	cell-based format	Scientific Literature
8.	ALA4133152	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of BzATP-induced ethidium iodide uptake after 30 mins by spectrofluorometric analysis	Mus musculus	3	ALA4130413	single protein format	Scientific Literature
9.	ALA4133153	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of BzATP-induced current at holding potential of -60 mV preincubated for 5 mins followed by BzATP addition measured after 5 mins by Whole cell patch-clamp analysis	Mus musculus	3	ALA4130413	single protein format	Scientific Literature
10.	ALA4133154	B	Antagonist activity at P2X7 receptor in LPS/IFNc-differentiated human THP-1 cells assessed as inhibition of ATP-induced IL-1beta release preincubated for 30 mins followed by LPS stimulation for 4 hrs using cells treated with ATP for 30 mins by ELISA	Homo sapiens	2	ALA4130413	cell-based format	Scientific Literature
11.	ALA4133155	B	Antagonist activity at P2X7 receptor in LPS/IFNc-differentiated Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced IL-1beta release preincubated for 30 mins followed by LPS stimulation for 4 hrs using cells treated with ATP for 15 mins by ELISA	Mus musculus	2	ALA4130413	assay format	Scientific Literature
12.	ALA4133156	B	Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced IL-1beta release preincubated for 30 mins followed by ATP addition measured after 30 mins by ELISA	Homo sapiens	2	ALA4130413	cell-based format	Scientific Literature
13.	ALA4133157	A	Drug metabolism assessed as CYP1A2 (unknown origin)-mediated metabolite formation	Homo sapiens	4	ALA4130413	single protein format	Scientific Literature
14.	ALA4133158	A	Drug metabolism assessed as CYP2C9 (unknown origin)-mediated metabolite formation	Homo sapiens	4	ALA4130413	single protein format	Scientific Literature
15.	ALA4133159	A	Drug metabolism assessed as CYP2C19 (unknown origin)-mediated metabolite formation	Homo sapiens	4	ALA4130413	single protein format	Scientific Literature
16.	ALA4133160	A	Drug metabolism assessed as CYP2D6 (unknown origin)-mediated metabolite formation	Homo sapiens	4	ALA4130413	single protein format	Scientific Literature
17.	ALA4133161	A	Drug metabolism assessed as CYP3A4 (unknown origin)-mediated metabolite formation	Homo sapiens	4	ALA4130413	single protein format	Scientific Literature
18.	ALA4133162	A	Drug metabolism assessed as UGT1A1 (unknown origin)-mediated metabolite formation	Homo sapiens	4	ALA4130413	single protein format	Scientific Literature
19.	ALA4133163	A	Drug metabolism assessed as UGT1A3 (unknown origin)-mediated metabolite formation	Homo sapiens	4	ALA4130413	single protein format	Scientific Literature
20.	ALA4133164	A	Drug metabolism assessed as UGT1A4 (unknown origin)-mediated metabolite formation	Homo sapiens	4	ALA4130413	single protein format	Scientific Literature