| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4151511 | B | Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux at 50 uM incubated for 5 mins by fluorescence based assay | Staphylococcus aureus | 44 | single protein format | Scientific Literature | ||
| 2. | ALA4151512 | B | Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluorescence based assay | Staphylococcus aureus | 44 | single protein format | Scientific Literature | ||
| 3. | ALA4151513 | A | Antimicrobial activity against Staphylococcus aureus SA-1199B expressing wild type norA and co-expressing GrlA A116E mutant by microdilution method | Staphylococcus aureus | 44 | organism-based format | Scientific Literature | ||
| 4. | ALA4151514 | B | Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as minimal potentiating drug concentration causing 8 fold reduction in ciprofloxacin MIC by microdilution method based Checkerboard assay | Staphylococcus aureus | 44 | single protein format | Scientific Literature | ||
| 5. | ALA4151515 | F | Synergistic potentiation of ciprofloxacin-induced antimicrobial activity against wild type Staphylococcus aureus ATCC 25923 at 0.78 to 100 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 21 | organism-based format | Scientific Literature | ||
| 6. | ALA4151516 | F | Synergistic potentiation of ciprofloxacin-induced antimicrobial activity against Staphylococcus aureus SA-1199 at 0.78 to 100 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 21 | organism-based format | Scientific Literature | ||
| 7. | ALA4151517 | B | Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as synergistic potentiation of ciprofloxacin-induced antimicrobial activity at 0.78 to 100 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 21 | single protein format | Scientific Literature | ||
| 8. | ALA4151519 | B | Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as synergistic potentiation of ciprofloxacin-induced antimicrobial activity by measuring reduction in ciprofloxacin MIC at 0.78 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 2 | single protein format | Scientific Literature | ||
| 9. | ALA4151520 | B | Inhibition of NorA in Staphylococcus aureus SA-K2378 assessed as synergistic potentiation of ciprofloxacin-induced antimicrobial activity at 0.78 to 100 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 7 | single protein format | Scientific Literature | ||
| 10. | ALA4151521 | F | Synergistic potentiation of ciprofloxacin-induced antimicrobial activity against norA deleted Staphylococcus aureus SA-K1902 at 0.78 to 100 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 7 | organism-based format | Scientific Literature | ||
| 11. | ALA4151522 | B | Inhibition of NorA in Staphylococcus aureus SA-K2378 assessed as synergistic potentiation of ciprofloxacin-induced antimicrobial activity at 0.78 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 3 | single protein format | Scientific Literature | ||
| 12. | ALA4151523 | A | Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by ATP bioluminescence assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 13. | ALA4151524 | A | Cytotoxicity in human THP1 cells assessed as reduction in cell viability incubated for 24 hrs by ATP bioluminescence assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 14. | ALA4151525 | A | Antimicrobial activity against Staphylococcus aureus ATCC 25923 by microdilution method | Staphylococcus aureus | 25 | organism-based format | Scientific Literature | ||
| 15. | ALA4151526 | T | Selectivity index, ratio of CC50 for human HepG2 cells to inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as minimal potentiating drug concentration causing 8 fold reduction in ciprofloxacin MIC by microdilution method based Checkerboard assay | 2 | assay format | Scientific Literature | |||
| 16. | ALA4151527 | T | Selectivity index, ratio of CC50 for human THP1 cells to inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as minimal potentiating drug concentration causing 8 fold reduction in ciprofloxacin MIC by microdilution method based Checkerboard assay | 1 | assay format | Scientific Literature | |||
| 17. | ALA4151528 | A | Antimicrobial activity against Staphylococcus aureus SA-1199B expressing wild type norA by microdilution method | Staphylococcus aureus | 25 | organism-based format | Scientific Literature | ||
| 18. | ALA4151529 | A | Antimicrobial activity against NorA deficient Staphylococcus aureus SA-K1902 by microdilution method | Staphylococcus aureus | 25 | organism-based format | Scientific Literature | ||
| 19. | ALA4151530 | A | Antimicrobial activity against NorA overexpressing Staphylococcus aureus SA-K2378 by microdilution method | Staphylococcus aureus | 25 | organism-based format | Scientific Literature | ||
| 20. | ALA4151531 | A | Antimicrobial activity against mepA deficient Staphylococcus aureus SA-K2885 by microdilution method | Staphylococcus aureus | 25 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!