# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4147382 | B | Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Homo sapiens | 9 | ALA4145500 | assay format | Scientific Literature | |
2. | ALA4147383 | B | Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Plasmodium falciparum | 9 | ALA4145500 | single protein format | Scientific Literature | |
3. | ALA4147384 | F | Antiparasitic activity against Plasmodium falciparum Dd2 clone MRA-150 synchronized ring stage after 48 hrs by PicoGreen dye based microfluorimetric analysis | Plasmodium falciparum | 9 | ALA4145500 | organism-based format | Scientific Literature | |
4. | ALA4147385 | B | Selectivity index, ratio of Ki for recombinant full length human G6PD to Ki for Plasmodium falciparum G6PD-6PGL | 9 | ALA4145500 | assay format | Scientific Literature | ||
5. | ALA4147388 | A | Cytotoxicity against human HepG2 cells assessed as cell survival at 0.2 to 1 mM after 24 hrs by EZ4U staining-based spectrophotometric analysis relative to control | Homo sapiens | 9 | ALA4145500 | cell-based format | Scientific Literature | |
6. | ALA5121899 | B | Binding affinity to human G6PD | Homo sapiens | 9 | ALA5120775 | single protein format | Scientific Literature | |
7. | ALA5121900 | B | Binding affinity to Plasmodium falciparum GluPho | Plasmodium falciparum | 9 | ALA5120775 | assay format | Scientific Literature | |
8. | ALA5121901 | B | Selectivity index, ratio of Ki for human G6PD to Ki for Plasmodium falciparum GluPho | 9 | ALA5120775 | assay format | Scientific Literature |