# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4148417 | B | Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cell membranes after 1 hr by Microbeta scintillation counting method | Homo sapiens | 17 | ALA4145534 | cell-based format | Scientific Literature | |
2. | ALA4148418 | B | Displacement of [3H]-8-OH-DPAT from human 5HT1AR expressed in HEK293 cell membranes after 1 hr by Microbeta scintillation counting method | Homo sapiens | 17 | ALA4145534 | cell-based format | Scientific Literature | |
3. | ALA4148419 | B | Displacement of [3H]-5-CT from human 5HT7BR expressed in HEK293 cell membranes after 1 hr by Microbeta scintillation counting method | Homo sapiens | 17 | ALA4145534 | cell-based format | Scientific Literature | |
4. | ALA4148420 | B | Displacement of [3H]-prazosin from alpha1-adrenergic receptor in rat brain cortex after 30 mins by Microbeta scintillation counting method | Rattus norvegicus | 17 | ALA4145534 | assay format | Scientific Literature | |
5. | ALA4148422 | B | Displacement of [3H]-CGP-12177 from beta1-adrenergic receptor in rat brain cortex after 1 hr by Microbeta scintillation counting method | Rattus norvegicus | 14 | ALA4145534 | assay format | Scientific Literature | |
6. | ALA4148423 | F | Antidepressant like activity in Swiss albino mouse assessed as immobility time at 5 mg/kg, ip administered 60 mins prior to test and measured last 4 mins of 6 mins test by forced swimming test (Rvb = 159.78 to 183.56 secs) | Mus musculus | 4 | ALA4145534 | organism-based format | Scientific Literature | |
7. | ALA4148424 | F | Antidepressant like activity in Swiss albino mouse assessed as immobility time at 10 mg/kg, ip administered 60 mins prior to test and measured last 4 mins of 6 mins test by forced swimming test (Rvb = 159.78 to 183.56 secs) | Mus musculus | 4 | ALA4145534 | organism-based format | Scientific Literature | |
8. | ALA4148425 | F | Antidepressant like activity in Swiss albino mouse assessed as immobility time at 20 mg/kg, ip administered 60 mins prior to test and measured last 4 mins of 6 mins test by forced swimming test (Rvb = 159.78 to 183.56 secs) | Mus musculus | 4 | ALA4145534 | organism-based format | Scientific Literature | |
9. | ALA4148430 | F | Anxiolytic-like activity in Swiss albino mouse assessed as number of punished crossings at 10 mg/kg, ip administered 60 mins prior to test and measured post 3 secs of electric shock by four-plate test (Rvb = 3.8 to 4 /min) | Mus musculus | 4 | ALA4145534 | organism-based format | Scientific Literature | |
10. | ALA4148431 | F | Anxiolytic-like activity in Swiss albino mouse assessed as number of punished crossings at 20 mg/kg, ip administered 60 mins prior to test and measured post 3 secs of electric shock by four-plate test (Rvb = 3.8 to 4 /min) | Mus musculus | 4 | ALA4145534 | organism-based format | Scientific Literature | |
11. | ALA4148432 | F | Anxiolytic-like activity in Swiss albino mouse assessed as number of punished crossings at 40 mg/kg, ip administered 60 mins prior to test and measured post 3 secs of electric shock by four-plate test (Rvb = 3.8 to 4 /min) | Mus musculus | 2 | ALA4145534 | organism-based format | Scientific Literature | |
12. | ALA4148436 | F | Antidepressant like activity in Swiss albino mouse assessed as decrease in immobility time at 20 mg/kg, ip administered 60 mins prior to test and measured last 4 mins of 6 mins test by forced swimming test relative to control | Mus musculus | 1 | ALA4145534 | organism-based format | Scientific Literature | |
13. | ALA4148439 | A | Effect on spontaneous locomotor activity in Swiss albino mouse at 20 mg/kg, ip administered 60 mins prior to test and measured for 3 to 6 mins | Mus musculus | 3 | ALA4145534 | organism-based format | Scientific Literature | |
14. | ALA4148440 | B | Selectivity ratio of Ki for human D2L receptor expressed in HEK293 cell membranes to Ki for human 5HT7BR expressed in HEK293 cell membranes | Homo sapiens | 3 | ALA4145534 | cell-based format | Scientific Literature |