# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4149394 | B | Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by LANCE assay | Homo sapiens | 13 | ALA4145565 | cell-based format | Scientific Literature | |
2. | ALA4329850 | A | Apparent permeability in pig LLC-PK1 cells at 1 uM after 3 hrs | Sus scrofa | 27 | ALA4325924 | cell-based format | Scientific Literature | |
3. | ALA4329852 | A | Ratio of drug level in liver to plasma in Wistar Han rat at 10 mg/kg, po administered via gavage measured after 4 hrs by LC-MS/MS analysis | Rattus norvegicus | 27 | ALA4325924 | organism-based format | Scientific Literature | |
4. | ALA4329853 | B | Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as substrates preincubated for 30 mins followed by substrates addition and measured after 2 hrs by TR-FRET assay | Homo sapiens | 27 | ALA4325924 | cell-based format | Scientific Literature | |
5. | ALA4329854 | B | Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as substrates preincubated for 30 mins followed by substrates addition and measured after 2 hrs by TR-FRET assay | Homo sapiens | 27 | ALA4325924 | cell-based format | Scientific Literature | |
6. | ALA4329855 | B | Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as substrates preincubated for 30 mins followed by substrates addition and measured after 2 hrs by TR-FRET assay | Homo sapiens | 27 | ALA4325924 | cell-based format | Scientific Literature |