# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4154392 | B | Displacement of [3H]Nalpha-methylhistamine from recombinant human H3 receptor expressed in HEK293 cells after 90 mins by liquid scintillation counting method | Homo sapiens | 26 | ALA4152242 | cell-based format | Scientific Literature | |
2. | ALA4154393 | B | Agonist activity at H1 receptor in guinea pig ileum assessed as induction of ileum contraction measured after 15 mins | Cavia porcellus | 1 | ALA4152242 | assay format | Scientific Literature | |
3. | ALA4154394 | B | Agonist activity at muscarinic receptor in guinea pig ileum assessed as induction of ileum contraction measured after 15 mins | Cavia porcellus | 1 | ALA4152242 | assay format | Scientific Literature | |
4. | ALA4154395 | B | Antagonist activity at H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced ileum contraction measured after 15 mins | Cavia porcellus | 2 | ALA4152242 | assay format | Scientific Literature | |
5. | ALA4154396 | B | Antagonist activity at muscarinic receptor in guinea pig ileum assessed as carbachol-induced ileum contraction measured after 15 mins | Cavia porcellus | 2 | ALA4152242 | assay format | Scientific Literature | |
6. | ALA4154397 | B | Competitive antagonist activity at H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced ileum contraction measured after 15 mins | Cavia porcellus | 1 | ALA4152242 | assay format | Scientific Literature | |
7. | ALA4154398 | F | Reversal of RAMH-induced dipsogenia in ip dosed Krf:(WI) WU rat assessed as inhibition of drinking response pretreated for 30 mins followed by RAMH stimulation for 20 mins measured for 30 mins | Rattus norvegicus | 1 | ALA4152242 | organism-based format | Scientific Literature | |
8. | ALA4154400 | F | Reversal of scopolamine-induced memory deficit in Albino Swiss CD-1 mouse assessed as increase in step through latency time at 2.5 to 30 mg/kg, ip treated for 1 hr prior to testing followed by scopolamine challenge measured after 30 mins by passive avoidance test | Mus musculus | 1 | ALA4152242 | organism-based format | Scientific Literature | |
9. | ALA4154401 | F | Reversal of scopolamine-induced memory deficit in Albino Swiss CD-1 mouse assessed as increase in step through latency time at 2.5 to 30 mg/kg, ip treated for 1 hr before training followed by scopolamine challenge 30 mins before training measured 24 hrs after training trial by passive avoidance test | Mus musculus | 1 | ALA4152242 | organism-based format | Scientific Literature | |
10. | ALA4154403 | F | Anticonvulsant activity in ip dosed maximal electroshock induced seizure TO mouse model assessed as suppression of tonic hind limb extension pretreated for 30 to 45 mins followed by maximal electroshock induction | Mus musculus | 1 | ALA4152242 | organism-based format | Scientific Literature | |
11. | ALA4154404 | A | Drug metabolism in human liver microsomes after 2 hrs by UPLC analysis | Homo sapiens | 1 | ALA4152242 | microsome format | Scientific Literature | |
12. | ALA4734937 | B | Binding affinity to human H3R | Homo sapiens | 9 | ALA4732109 | single protein format | Scientific Literature |