# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4137466 | B | Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assay | Homo sapiens | 39 | single protein format | Scientific Literature | ||
2. | ALA4137467 | B | Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assay | Homo sapiens | 39 | single protein format | Scientific Literature | ||
3. | ALA4137468 | A | Permeability of the compound at 50 uM after 18 hrs by PAMPA | 18 | assay format | Scientific Literature | |||
4. | ALA4137469 | F | Growth inhibition of human CEMO1 cells after 48 hrs by MTS assay | Homo sapiens | 13 | assay format | Scientific Literature | ||
5. | ALA4137472 | F | Growth inhibition of human LAL-CUN-2 cells after 48 hrs by MTS assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
6. | ALA4137475 | F | Growth inhibition of human OCI-LY3 cells after 48 hrs by MTS assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
7. | ALA4137477 | B | Inhibition of recombinant human GLP using histone H3 peptide as substrate after 120 mins in presence of [3H]SAM by radiometric assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA4137478 | F | Growth inhibition of human OCI-LY10 cells after 48 hrs by MTS assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
9. | ALA4137480 | F | Growth inhibition of human MV4-11 cells after 48 hrs by MTS assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
10. | ALA4137481 | A | Growth inhibition of human THLE2 cells after 72 hrs by MTS assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
11. | ALA4137486 | B | Inhibition of recombinant human N-terminal GST-tagged DNMT3A (1 to 913 residues) expressed in baculovirus infected Sf9 cells at 10 uM relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA4137487 | B | Inhibition of recombinant mouse N-terminal His/C-terminal FLAG-tagged DNMT3B (2 to 859 residues) expressed in baculovirus infected Sf9 cells at 10 uM relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
13. | ALA4137488 | B | Inhibition of G9a in human MV4-11 cells assessed as reduction in H3K9me2 level after 48 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4137489 | B | Inhibition of DNMT1 in human MV4-11 cells assessed as reduction in global DNA methylation at 50 nM after 48 hrs by LC-MS/MS method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA4137490 | B | Inhibition of DNMT1 in human MV4-11 cells assessed as reduction in global DNA methylation at 100 to 1000 nM after 48 hrs by LC-MS/MS method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4137491 | B | Inhibition of DNMT1 in human MV4-11 cells assessed as reduction in global DNA methylation at 10 to 50 nM after 48 hrs by MethylationEPIC BeadChip microarray analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA4137492 | A | Inhibition of CYP1A2 in human liver microsomes at 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis relative to control | Homo sapiens | 4 | microsome format | Scientific Literature | ||
18. | ALA4137493 | A | Inhibition of CYP2C9 in human liver microsomes at 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis relative to control | Homo sapiens | 4 | microsome format | Scientific Literature | ||
19. | ALA4137494 | A | Inhibition of CYP2C19 in human liver microsomes at 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis relative to control | Homo sapiens | 4 | microsome format | Scientific Literature | ||
20. | ALA4137495 | A | Inhibition of CYP2D6 in human liver microsomes at 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis relative to control | Homo sapiens | 4 | microsome format | Scientific Literature |