| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4151582 | B | Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accumulation assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
| 2. | ALA4151583 | B | Inhibition of ABCB1 in human A2780adr cells at 10 uM preincubated for 30 mins before calcein AM addition by calcein AM assay relative to cyclosporine A | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 3. | ALA4151584 | B | Inhibition of ABCC1 in human H69AR cells at 10 uM preincubated for 30 mins before calcein AM addition by calcein AM assay relative to cyclosporine A | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 4. | ALA4151585 | A | Intrinsic cytotoxicity in MDCK2 cells overexpressing BCRP assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
| 5. | ALA4151586 | A | Intrinsic cytotoxicity in parental MDCK2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
| 6. | ALA4151587 | T | Therapeutic index, ratio of GI50 for intrinsic cytotoxicity in MDCK2 cells overexpressing BCRP to IC50 for inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells | 15 | cell-based format | Scientific Literature | |||
| 7. | ALA4151588 | B | Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells overexpressing BCRP assessed as enhancement of SN-38-induced cytotoxicity incubated for 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA4151589 | B | Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells overexpressing BCRP assessed as enhancement of SN-38-induced cytotoxicity at 100 uM incubated for 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA4151590 | A | Intrinsic cytotoxicity in parental MDCK2 cells assessed as inhibition of cell growth at incubated for 72 hrs by MTT assay relative to untreated control | Canis lupus familiaris | 5 | cell-based format | Scientific Literature |
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