# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4157343 | B | Binding affinity of F1F0-ATP synthase c subunit in human HeLa cells at 60 to 80 degC after 30 mins by cellular thermal shift assay | Homo sapiens | 1 | ALA4152345 | cell-based format | Scientific Literature | |
2. | ALA4157344 | B | Inhibition of F1F0-ATP synthase subunit C in human HeLa cells assessed as reduction of ionomycin-induced Ca2+ mediated mPTP opening at 1 uM preincubated for 30 secs followed by ionomycin addition by calcein-cobalt based assay relative to control | Homo sapiens | 25 | ALA4152345 | cell-based format | Scientific Literature | |
3. | ALA4157345 | B | Inhibition of Inhibition of F1F0-ATP synthase subunit C in SV129 mouse liver mitochondria assessed as reduction of Ca2+ induced mPTP opening by measuring reduction in mitochondrial swelling at 1 uM measured after 10 mins relative to control | Mus musculus | 5 | ALA4152345 | mitochondrion format | Scientific Literature | |
4. | ALA4157346 | A | Drug uptake in human HeLa cells mitochondrial fraction by HPLC-HRMS analysis | Homo sapiens | 2 | ALA4152345 | mitochondrion format | Scientific Literature | |
5. | ALA4157347 | A | Drug uptake in human HeLa cells endoplasmic reticulam fraction by HPLC-HRMS analysis | Homo sapiens | 2 | ALA4152345 | subcellular format | Scientific Literature | |
6. | ALA4157348 | A | Drug uptake in human HeLa cells cytosolic fraction by HPLC-HRMS analysis | Homo sapiens | 2 | ALA4152345 | subcellular format | Scientific Literature | |
7. | ALA4157361 | B | Binding affinity of F1F0-ATP synthase c subunit in isolated mitochondria of human HeLa cells after 30 mins by UPLC-XEVO-TQD analysis | Homo sapiens | 1 | ALA4152345 | mitochondrion format | Scientific Literature | |
8. | ALA4157363 | A | Drug uptake in human HeLa cells mitochondrial fraction assessed as retention time by HPLC-HRMS analysis | Homo sapiens | 1 | ALA4152345 | mitochondrion format | Scientific Literature | |
9. | ALA4157364 | B | Binding affinity of ATP5A in human HeLa cells assessed as melting temperature after 30 mins by cellular thermal shift assay | Homo sapiens | 1 | ALA4152345 | cell-based format | Scientific Literature | |
10. | ALA4157365 | A | Reduction in mitochondrial ATP content in human HeLa cells expressing mitochondrially targeted Photinus pyralis luciferase at 1 uM by luciferin-luciferase assay | Homo sapiens | 4 | ALA4152345 | cell-based format | Scientific Literature | |
11. | ALA4157366 | A | Reduction in mitochondrial ATP content in human HeLa cells expressing mitochondrially targeted Photinus pyralis luciferase at 1 uM in presence of 100 um histamine by luciferin-luciferase assay | Homo sapiens | 4 | ALA4152345 | cell-based format | Scientific Literature |