1. ALA4157383 F Antiviral activity against wild type HIV1 infected in human MT2 cells after 4 to 5 days by dual luciferase reporter gene assay Human immunodeficiency virus 1 32 ALA4152347 organism-based format Scientific Literature 2. ALA4157384 F Antiviral activity against wild type HIV1 infected in human MT2 cells after 4 to 5 days in presence of 10% FBS and 40% human serum albumin by dual luciferase reporter gene assay Human immunodeficiency virus 1 15 ALA4152347 organism-based format Scientific Literature 3. ALA4157385 F Antiviral activity against HIV1 expressing gag V370A mutant infected in human MT2 cells after 4 to 5 days by dual luciferase reporter gene assay Human immunodeficiency virus 1 26 ALA4152347 organism-based format Scientific Literature 4. ALA4157386 F Antiviral activity against HIV1 expressing gag delta V370 mutant infected in human MT2 cells after 4 to 5 days by dual luciferase reporter gene assay Human immunodeficiency virus 1 29 ALA4152347 organism-based format Scientific Literature 5. ALA4157387 A Cytotoxicity against human MT2 cells assessed as reduction in cell viability Homo sapiens 32 ALA4152347 cell-based format Scientific Literature 6. ALA4157388 A AUC (0 to 6 hrs) in Sprague-Dawley rat at 5 mg/kg, po administered via gavage Rattus norvegicus 8 ALA4152347 organism-based format Scientific Literature 7. ALA4157389 A AUC (0 to 24 hrs) in Sprague-Dawley rat at 5 mg/kg, po administered via gavage Rattus norvegicus 13 ALA4152347 organism-based format Scientific Literature 8. ALA4157392 F Antiviral activity against HIV1 expressing gag V362I mutant infected in human MT2 cells after 4 to 5 days by dual luciferase reporter gene assay Human immunodeficiency virus 1 2 ALA4152347 organism-based format Scientific Literature 9. ALA4157393 F Antiviral activity against HIV1 expressing gag Q369H mutant infected in human MT2 cells after 4 to 5 days by dual luciferase reporter gene assay Human immunodeficiency virus 1 2 ALA4152347 organism-based format Scientific Literature 10. ALA4157394 F Antiviral activity against HIV1 expressing gag V370M mutant infected in human MT2 cells after 4 to 5 days by dual luciferase reporter gene assay Human immunodeficiency virus 1 2 ALA4152347 organism-based format Scientific Literature 11. ALA4157395 F Antiviral activity against HIV1 expressing gag V370A/delta T371 double mutant infected in human MT2 cells after 4 to 5 days by dual luciferase reporter gene assay Human immunodeficiency virus 1 2 ALA4152347 organism-based format Scientific Literature 12. ALA4157396 F Antiviral activity against HIV1 expressing gag T371A mutant infected in human MT2 cells after 4 to 5 days by dual luciferase reporter gene assay Human immunodeficiency virus 1 2 ALA4152347 organism-based format Scientific Literature 13. ALA4157397 F Antiviral activity against HIV1 expressing gag delta V371 mutant infected in human MT2 cells after 4 to 5 days by dual luciferase reporter gene assay Human immunodeficiency virus 1 2 ALA4152347 organism-based format Scientific Literature 14. ALA4157398 B Binding affinity to wild type HIV1 gag polyprotein containing viral like particle Human immunodeficiency virus 1 2 ALA4152347 single protein format Scientific Literature 15. ALA4157399 B Binding affinity to HIV1 gag polyprotein V362I mutant containing viral like particle Human immunodeficiency virus 1 2 ALA4152347 single protein format Scientific Literature 16. ALA4157400 B Binding affinity to HIV1 gag polyprotein V370A mutant containing viral like particle Human immunodeficiency virus 1 2 ALA4152347 single protein format Scientific Literature 17. ALA4157401 B Binding affinity to HIV1 gag polyprotein delta V370 mutant containing viral like particle Human immunodeficiency virus 1 2 ALA4152347 single protein format Scientific Literature 18. ALA4157403 P Aqueous solubility of the compound 6 ALA4152347 small-molecule physicochemical format Scientific Literature 19. ALA4157406 F Antiviral activity against HIV1 expressing gag A364V mutant Human immunodeficiency virus 1 2 ALA4152347 organism-based format Scientific Literature 20. ALA4157469 A Half life in rat liver microsomes at 0.5 uM after 1 hr in presence of NADPH by LC-MS/MS analysis Rattus norvegicus 32 ALA4152347 microsome format Scientific Literature