# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4144917 | B | Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretreated for 15 mins followed by substrate addition measured after 60 mins by CPM dye based fluorescence assay | Homo sapiens | 23 | ALA4138301 | assay format | Scientific Literature | |
2. | ALA4144918 | P | Kinetic solubility of the compound in pION buffer at pH 7.4 measured after 18 hrs | 28 | ALA4138301 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4144920 | B | Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as substrates pretreated for 30 mins in presence of C10-DAG followed by [3H]-labelled decanoyl-CoA addition measured after 60 mins by microbeta counting method | Homo sapiens | 10 | ALA4138301 | assay format | Scientific Literature | |
4. | ALA4144921 | B | Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as substrates pretreated for 30 mins in presence of C10-DAG followed by [3H]-labelled decanoyl-CoA addition measured after 60 mins by microbeta counting method | Rattus norvegicus | 6 | ALA4138301 | assay format | Scientific Literature | |
5. | ALA4144922 | B | Inhibition of DGAT1 in mouse C2C12 cells at 300 nM using [14C] oleic acid as substrate measured after 20 mins by phosphorimaging method relative to control | Mus musculus | 6 | ALA4138301 | cell-based format | Scientific Literature |