| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4151582 | B | Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accumulation assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
| 2. | ALA4151583 | B | Inhibition of ABCB1 in human A2780adr cells at 10 uM preincubated for 30 mins before calcein AM addition by calcein AM assay relative to cyclosporine A | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 3. | ALA4151584 | B | Inhibition of ABCC1 in human H69AR cells at 10 uM preincubated for 30 mins before calcein AM addition by calcein AM assay relative to cyclosporine A | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 4. | ALA4151585 | A | Intrinsic cytotoxicity in MDCK2 cells overexpressing BCRP assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
| 5. | ALA4151586 | A | Intrinsic cytotoxicity in parental MDCK2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
| 6. | ALA4151587 | T | Therapeutic index, ratio of GI50 for intrinsic cytotoxicity in MDCK2 cells overexpressing BCRP to IC50 for inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells | 15 | cell-based format | Scientific Literature | |||
| 7. | ALA4151595 | B | Activation of ATPase activity of ABCG2 (unknown origin) expressed in High Five insect cell membranes by ascorbic acid ammonia molybdate reaction based colorimetry | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA4151596 | B | Activation of ATPase activity of ABCG2 (unknown origin) expressed in High Five insect cell membranes by ascorbic acid ammonia molybdate reaction based colorimetry relative to vanadate-sensitive basal activity | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 9. | ALA4151599 | B | Non-competitive inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accumulation assay based Lineweaver-Burk plot analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA4151603 | B | Mixed type inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accumulation assay based Cornish-Bowden plot to analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4151604 | B | Binding affinity to ABCG2 in human PLB-985 cells assessed as 5D3 labelling level at 10 uM by 5D3 antibody binding assay relative to Ko143 | Homo sapiens | 8 | cell-based format | Scientific Literature |
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