| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4139218 | B | Displacement of [3H]prazosin from human alpha1A adrenoceptor expressed in CHO cell membranes after 30 mins | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 2. | ALA4139219 | B | Displacement of [3H]prazosin from human alpha1B adrenoceptor expressed in CHO cell membranes after 30 mins | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 3. | ALA4139220 | B | Displacement of [3H]prazosin from human alpha1D adrenoceptor expressed in CHO cell membranes after 30 mins | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 4. | ALA4139221 | F | Antiproliferative activity against human NCI60 cells at 10 uM after 48 hrs by SRB assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA4139222 | F | Antiproliferative activity against human DU145 cells at 10 uM after 48 hrs by SRB assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4139223 | F | Growth inhibition of human PC3 cells at 10 uM after 48 hrs by SRB assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4139224 | F | Antiproliferative activity against human DU145 cells after 120 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4139225 | F | Antiproliferative activity against human PC3 cells after 120 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4139226 | F | Antiproliferative activity against human LNCAP cells after 120 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4139227 | B | Selectivity ratio of Ki for human alpha1A adrenoceptor to Ki for human alpha1B adrenoceptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA4139228 | B | Selectivity ratio of Ki for human alpha1D adrenoceptor to Ki for human alpha1B adrenoceptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4139229 | F | Induction of necrosis in human LNCAP cells assessed as loss of plasma membrane integrity at 1 to 10 uM after 24 hrs by trypan blue staining-based Neubauer hemocytometric method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4139230 | T | Selectivity index, ratio of cytotoxic concentration for HGF cells to IC50 for human LNCAP cells | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA4139231 | T | Selectivity index, ratio of cytotoxic concentration for HGF cells to IC10 for human LNCAP cells | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4139232 | F | Induction of apoptosis in human LNCAP cells assessed as increase in DNA fragmentation at 1 to 10 uM after 24 hrs by spectrophotometer relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4139233 | F | Induction of apoptosis in human LNCAP cells assessed as increase in DNA fragmentation after 24 hrs by spectrophotometer | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4139235 | F | Antioxidant activity in human LNCAP cells assessed as inhibition of t-BuOOH-induced ROS level after 30 mins by DCFH-DA dye-based spectrofluorometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4139236 | F | Antioxidant activity in human LNCAP cells assessed as inhibition of t-BuOOH-induced ROS level at 1 to 10 uM after 30 mins by DCFH-DA dye-based spectrofluorometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4139237 | F | Antioxidant activity in human LNCAP cells assessed as inhibition of t-BuOOH-induced ROS level at 1 to 10 uM after 24 hrs by DCFH-DA dye-based spectrofluorometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4139238 | F | Induction of ROS generation in human LNCAP cells after 24 hrs by DCFH-DA dye-based spectrofluorometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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